Lecture 8 - Cranial Nerves V and VII Flashcards

1
Q

The trigeminal nerve (CN V) consists of what 2 types of nuclei?

A
  • somatic sensory

- branchial motor

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2
Q

The somatic sensory trigeminal nerve (CN V) nuclei whose peripheral fibers supply the skin and deep tissues of the head and dura are the ______ and _____ _____ nuclei. The somatic sensory CN V nucleus that supplies peripheral muscle spindles and other mechanoreceptors is the _______ nucleus.

A
  • spinal
  • main sensory
  • mesencephalic
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3
Q

The branchial motor trigeminal nerve (CN V) nucleus whose peripheral fibers supply the MOM, tensor tympani, and several other muscles is the ______ ______ nucleus. It forms the _____ limb of the jaw-jerk reflex.

A
  • trigeminal motor
  • efferent
  • innervated muscles = “MOM & the tensor twins.” These are the muscles of mastication, tensor tympani, tensor veli palatini, as well as the mylohyoid and anterior belly of the digastric muscles
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4
Q

What 4 types of sensory information does the trigeminal nerve (CN V) transmit to the cortex, cerebellum, and reticular formation?

A
  • tactile
  • proprioceptive
  • pain
  • temperature
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5
Q

The trigeminal nerve (CN V) has 3 branches. The sensory division that supplies the upper face is the ______ division (V1). The sensory division that supplies the middle face is the ________ division (V2). The mixed sensory and motor division that supplies the lower face is the ______ division (V3).

A
  • ophthalmic
  • maxillary
  • mandibular
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6
Q

Three of the trigeminal nuclei (mesencephalic, main sensory, trigeminal motor) can be viewed from an XS of the middle _____.

A

pons

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7
Q

The trigeminal SPINAL nucleus sends ascending [contralateral/bilateral] projections to the _____ _____ nucleus of the thalamus. The trigeminal MAIN SENSORY nucleus sends [contralateral/bilateral] projections to the same place. Both then travel through the internal capsule to the ________ ______ of the parietal lobe.

A
  • contralateral
  • ventral posteromedial (VPM)
  • bilateral
  • postcentral gyrus
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8
Q

Sensory fibers of the trigeminal nerve serve the face, oral cavity, teeth, and meninges. These areas transmit sensory info to the trigeminal ______. These then send feedback to the ____ _____ _____ nucleus. Senses included are _____ touch and ______.

A
  • ganglion
  • trigeminal main sensory
  • discriminative
  • vibration
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9
Q

The main trigeminal sensory nucleus is at mid-____ level, and sends a thick ______ of cells through much of the brainstem.

A
  • pons

- column

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10
Q

The trigeminal main sensory nucleus is homologous to the _______ _______ nuclei that receives proprioceptive info from the appendicular skeleton.

A
  • posterior column (PCML)
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11
Q

The trigeminal main sensory nucleus has 2 pathways. The [crossed/uncrossed] pathway joins the medial lemniscus on its way to the ______ _______ nucleus of the thalamus. The [crossed/uncrossed] dorsal trigeminal tract representing the oral cavity goes to the _____ _____ nucleus of the thalamus.

A
  • crossed
  • ventral posterolateral (VPL)
  • uncrossed
  • ventral posteromedial (VPM)
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12
Q

The trigeminal spinal nucleus senses ______, ____ ____, and ________. It is directly ______ of the trigeminal ______ _______ nucleus, and uses similar pathways.

A
  • pain
  • crude touch
  • temperature
  • inferior
  • main sensory
  • homologous to Lissauer’s tract of the anterolateral spinal pathway (ALP) that transmits the same senses
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13
Q

The trigeminal spinal nucleus is divided into 3 parts based on histology. (Rostral to Caudal)

  1. _____ nucleus: main sensory nucleus to pontomedullary junction
  2. _____ nucleus: pontomedullary junction to obex
  3. _____ nucleus: obex to spinal cord
A
  1. oral
  2. interpolar
  3. caudal
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14
Q

As part of the spinal trigeminal nucleus the _____ ______, receives input from intraoral and perioral structures. The part of the nucleus directly inferior to this that activates trigemino-autonomic reflexes is the ____ ______ proper. The most inferior of all 3 portions is responsible for pain, crude touch, and temperature sensation - the _____ ______.

A
  • pars oralis
  • pars interpolaris
  • pars caudalis
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15
Q

Where the spinal trigeminal nucleus transitions from the pars interpolaris to the pars caudalis, there is a lack of ______ organization, and the region responds to and possibly supresses _____ from many areas served by the trigeminal nerve (CN V).

A
  • somatotopic

- pain

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16
Q

The pars caudalis serves both superficial structures like the ______ _____ and teeth, and deep muscles such as the _______, and the ____. The convergence of these structures may be a basis for referred ______.

A
  • oral cavity
  • MOM (muscles of mastication)
  • TMJ
  • pain
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17
Q

Spinal trigeminal fibers join the ______ tract and terminate in the VPM.

A

spinothalamic

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18
Q

Pars caudalis has a ____ structure with ______ organization. This makes it look like an “_____ _____” representation from rostral to caudal of the peripheral face. Mostly _____ fibers are present here.

A
  • laminar (lamina II)
  • somatotopic
  • onion peel
  • pain
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19
Q

The pars caudalis is in _______ ___ of the substantia gelatinosa, and contains both excitatory and inhibitory interneurons. It receives afferents from CN ____, ___, and ____ for the near ear.

A
  • lamina II
  • VII
  • IX
  • X
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20
Q

The “onion-like” somatotopic arrangement of the pars caudalis is arranged as follows:

  • mandibular division (V3): ______
  • ophthalmic (V1): _______
  • maxillary (V2): _______
A
  • dorsal
  • ventral
  • in between
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21
Q

Due to the onion-like distribution of sensory loss, the more ______ a spinal trigeminal tract injury, the more sensory function is preserved around the mouth.

A

caudal

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22
Q

In the tooth pulp (V3), 70-80% of fibers are ____ and ___ for fast and slow pain. 20-30% are _____ for touch and pressure (faster) from the inferior alveolar nerves into the predentin and dentinal tubules of teeth.

A
  • C
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23
Q

In tooth pulp, the sensory fibers project to the trigeminal _____ _____ nucleus and trigeminal _____ nucleus. In the latter, their projections decrease from the pars oralis to the inferior pars caudalis. They also project to the upper cervical _____ ____.

A
  • main sensory
  • spinal
  • spinal cord
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24
Q

Brief episodes of excruciating pain caused by one or more divisions of the trigeminal nerve is called _____ _____. It is most common in the ____ division.

A
  • trigeminal neuralgia

- mandibular (V3)

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25
Q

Trigeminal neuralgia is often triggered by _____ stimuli. There [is/is not] sensory trouble between attacks. Another possible trigger may be trigeminal compression by a _____ _____ or ______. Possible treatment is cutting the nerve root, which results in a loss of ______ related to the cut root.

A
  • tactile
  • is not
  • blood vessel
  • tumor
  • everything (all sensation, not just pain)
26
Q

Surgical cutting for trigeminal neuralgia is dangerous because it compromises medullary _____ and _____ centers.

A
  • cardiovascular

- respiratory

27
Q

Vascular-related trigeminal neuralgia is usually the result of the ______ ______ artery. The artery can be reoriented with surgical padding to ______ the trigeminal nerve.

A
  • superior cerebellar

- decompress

28
Q

The jaw-jerk reflex is mediated by the trigeminal _____ nucleus.

A

motor

29
Q

Chewing movements are mediated by the ____-_____ nucleus directly superior to the trigeminal motor nucleus.

A

supra-trigeminal

30
Q

The trigeminal _______ nucleus is responsible for ______ (spatial orientation) of the MoM, and for pressure/tension on the ______ ligaments.

A
  • mesencephalic
  • proprioception
  • periodontal
31
Q

Since the trigeminal mesencephalic nucleus is sensory for proprioception, it projects to the efferent nuclei responsible for mastication: trigeminal _____ nucleus, and _____-______ nucleus (masticatory generator).

A
  • motor

- supra-trigeminal

32
Q

The trigeminal ________ nucleus controls the occlusal vertical dimension between the maxilla and mandible.

A

mesencephalic

33
Q

Cell bodies of the trigeminal mesencephalic nucleus are ______.

A

unipolar

34
Q

Trigeminal (CN V) Nuclei Summary:

  1. Mesencephalic nucleus: ______ myelination, homologue of the ____ ____ _____ _______ pathway. Function:_______
  2. Main sensory nucleus: _______ myelination, homologue of the _____ _____ _____ _________ pathway. Function:_______ touch
  3. Spinal nucleus: ______ myelination, homologue of the ________ system. Functions: ____, ___ touch, _______
A
    • heavy
    • posterior column medial lemniscal (PCML)
    • proprioception

2.

  • heavy
  • posterior column medial lemniscal (PCML)
  • discriminative
    • light
    • anterolateral
    • pain, crude touch, temperature
35
Q

The trigeminal motor nucleus has _____ _____ cell bodies. It terminates in the muscles of mastication, and functions to ______ the mandible.

A
  • branchial motor

- close

36
Q

Trigeminal motor nuclei lesions will cause weakened jaw _____, and will cause the open jaw to deviate [away from/toward] the side of the lesion.

A
  • closure

- toward

37
Q

The _________ nucleus is actually part of the reticular formation.

A

supra-trigeminal

38
Q

The supra-trigeminal nucleus is the _____ _____ ______ for mastication.

A

rhythmic pattern generator

39
Q

What are the 4 muscles of mastication?

A
  • temporalis (closing)
  • masseter (closing)
  • medial pterygoid (closing)
  • lateral pterygoid (opening)
40
Q

The jaw-jerk reflex is ________, or has only one synapse. It is activated by a downward tap on the chin that stretches the _______ muscles. The afferent limb of the trigeminal _________ nucleus receives the signal, while the efferent limb of the trigeminal _______ nucleus triggers mandibular closure. Damage to _____ ____ _____ enhances this reflex.

A
  • monosynaptic
  • masseter
  • mesencephalic
  • motor
  • upper motor neurons (UMN)
41
Q

What 4 types of nuclei are part of the facial nerve?

A
  • somatic sensory (SS)
  • visceral sensory (VS)
  • visceral motor (VM)
  • branchial motor (BM)
42
Q

The facial nerve (CN VII):

  • ______ _____ nucleus: pairs with the geniculate ganglion and serves the outer ear
  • Nucleus of ______ _____: pairs with geniculate ganglion, serves the taste buds/anterior 2/3 of tongue, parts of nasal cavity and soft palate
  • _____ ______ nucleus: pairs with submandibular & pterygopalatine ganglia, serves the following glands: submandibular, sublingual, nasal, palatine, lacrimal
  • ______ _____ nucleus: serves muscles of facial expression and the stapedius
A
  • spinal trigeminal (SS)
  • solitary tract
  • superior salivatory
  • facial motor
43
Q

The facial nerve (CN VII) has many functions. The muscles of _____ _____ close the eyes and lips. The volume of sounds are modulated by the _____ muscle. The anterior 2/3 of the tongue is provided with ______. The eyes are provided with tears through _______, and the sublingual/submandibular/parotid glands are stimulated to ______.

A
  • facial expression
  • stapedius
  • taste
  • lacrimation
  • salivate
44
Q

Somatic sensory fibers of the facial nerve supply the skin of the outer ____. Fibers enter the dorsomedially situated _____ _____ tract.

A
  • ear

- spinal trigeminal

45
Q

The facial _____ ______ nuclei supply the muscles of facial expression.

A

branchial motor

46
Q

Motor neurons to _____ facial muscles mainly innervated by contralateral cortex, but ______ facial muscles innervated bilaterally. Unilateral damage to the _________ pathway results in inability to smile or bare teeth symmetrically.

A
  • lower
  • upper
  • corticobulbar
47
Q

Corticobulbar lesions results in selective weakness of _____ facial muscles.

A

lower

48
Q

Paresis of facial muscles above and below the eyes, localized on one side of the face, leading to reduced salivation & lacrimation and hyperacusis of the stapedius is known as ______ ______.

A

Bell’s Palsy

49
Q

If the cornea is touched, both eyes blink. This is known as the _____ ______ reflex. The _____ limb of this reflex sends information from the trochlear nerve to the trigeminal spinal nucleus. The trigeminal spinal nucleus & reticular formation then stimulate the _______ limb through bilateral projections of the ______ nerve. This can be used as a clinical test for cranial nerves ___ and ___.

A
  • corneal blink
  • afferent
  • efferent
  • facial
  • V
  • VII
50
Q

The jaw _____ reflex is done when food comes into contact with oral membranse. The jaw ______ reflex is done when periodontal ligament afferents are activated by dental occlusion. The latter receives input from the trigeminal nerve about proprioception of jaw muscles (_____ ______ nucleus), tactile information regarding food in the mouth (______ ______ nucleus), and pain information (_____ _____ nucleus). The _____ nerve then sends output to the MoM.

A
  • closing
  • opening
  • trigeminal mesencephalic
  • trigeminal main
  • trigeminal spinal
  • facial
51
Q

The receptors for blinking reflexes in response to light are done in the _____. For noise, the receptors are in the _____. For sound attentuation, receptors are in the ____.

A
  • retina
  • cochlea
  • cochlea
52
Q

Afferents for reflexes:

  • Blink to light: _____ nerve
  • Blink to sound: _____ nucleus
  • Sound attenuation: _____ nucleus
A
  • optic
  • cochlear
  • cochlear
53
Q

Presynaptic fibers for reflexes:

  • Blink to light: _______ ______
  • Blink to sound: _______ ______
  • Sound attenuation: ______ ______ ______
A
  • superior colliculus
  • inferior colliculus
  • superior olivary nucleus (pons)
54
Q

Postsynaptic fibers for reflexes synapse a 2nd time:

  • Blink to light: ______ nucleus
  • Blink to sound: _______ nucleus
  • Sound attenuation: ______ nucleus
A
  • facial
  • facial
  • facial
55
Q

Muscles used for CN VII related reflexes:

  • Blink to light: _____ ______
  • Blink to sound: _____ ______
  • Sound attenuation: _________
A
  • orbicularis oculi
  • orbicularis oculi
  • stapedius
56
Q

Taste isn’t just due to taste bud information, but chemical stimulation of _______ receptors. Chemosensitive and somatosensory reception of food vapors on nerve endings of CN ___, ___, and ____ also help generate taste.

A
  • olfactory
  • V (trigeminal)
  • IX (glossopharyngeal)
  • X (vagus)
57
Q

The average tongue has about ______ taste buds, but the number of papillae and taste buds is highly variable. This accounts for the vast differences of tastes amongst people.

A

5,000

58
Q

Situated directly between the facial (CN VII) and vestibulocochlear nerves (CN VIII) where they project from the brainstem is the ______ ______.

A

nervus intermedius (intermediate nerve)

59
Q

All sensory input for taste, regardless of initially ganglionic synapse, eventually goes to the facial nerve’s nucleus of the ______ ______.

A

solitary tract

60
Q

1° gustatory afferents travel to the _______ tract to synapse. 2° fibers then either perform the ______ or _____ reflexes, or project uncrossed to the thalamus VPM, then the ______ cortex of the insula. This then projects to the orbitofrontal cortex with olfactory information, then to the amygdala, and finally to the _____ system.

A
  • solitary
  • swallowing
  • salivation
  • gustatory
  • limbic