Lecture 5 - Descending Motor Systems Flashcards
Upper motor neurons (UMN) originate in the motor region of the _____ ______ or the ________ and synapse on lower motor neurons.
- cerebral cortex
- brainstem
Lower motor neurons (LMN) originate in the ______ ______ gray matter or _____ ____ _____ of the spinal cord and are the last in a chain of neurons.
- anterior horn
- anterior nerve roots
Lower motor neurons (LMN) innervate _______ muscle, and signal muscle ________.
- striated
- contraction
Lower Motor Neurons:
Extrafusal muscle fibers use _____ motor neurons. Intrafusal muscle fibers use ______ motor neurons.
- alpha
- gamma
LMN lesions can result in loss of muscle tone called ______.
atonia
LMN lesions can result in loss of myotatic (knee jerk) reflex called _______.
areflexia
LMN lesions can result in inability of muscles to contract called _____ ______.
flaccid paralysis
LMN lesions can result in spontaneous muscle contractions called ________.
fasciculations
LMN lesions can result in loss of muscle tissue called _____.
atrophy
LMN lesions can result in irregular contractions of individual muscle fibers called _______.
fibrillations
UMN lesions result in _____ _______.
spastic paralysis (paresis)
UMN lesions resulting in increased resting muscle tension called _____.
hypertonia
UMN lesions resulting in twitching/spastic reflexes called ________.
hyperreflexia
UMN lesions may result in a characteristic upward extension of the toes (instead of flexion) upon stimulation of the plantar surface; this is called the _______ sign.
Babinski
Lesions on LMN result in ______ atrophy, while UMN lesions result in _____ atrophy.
- severe
- mild
As a result of UMN lesions, rapid series of alternate muscle contractions in response to the stretching of a muscle is known as a ______.
clonus
One LMN axon in the ventral root divides into many terminal _____ to innervate a muscle. Each of these ends at one _____ _____ _____.
- branches
- neuromuscular junction (NMJ)
LMN controlling axial muscles are _____ to those controlling distal muscles. Neurons controlling flexors are ______ to the extensor group.
- medial
- posterior
1 motor neuron + all myofibers it innervates = ____ ____.
motor unit
TRUE or FALSE:
A larger/less specific muscle has more myofibers per motor unit.
TRUE. More specific/smaller muscles have fewer fibers per motor unit.
Ex: Extraocular = 10 myofibers/unit; Gastrocnemius = 1,000/unit
3 Types of muscle fibers:
- _____ fibers contract weakly for long periods of time.
- _____ fibers contract strongly for short & long periods.
- _____ fibers contract very strongly for very short times.
- There [is/is not] mixing of the different myofibers.
- standing
- running
- jump
- is not
Type ___ muscles are for sustained weight/force bearing, and high in lipids and mitochondria, slow twitch, low glycogen. (duck breast)
Type ___ muscles are for sudden movements, low in lipids/mitochondria, fast twitch, high glycogen. (turkey breast)
- I
- II
- “one (type 1) slow (twitch) fat (lipid-rich) red (appearance) ox (oxidative, mitochondria-rich)”