Lecture 8 - Cell Communication and Signalling

Question 1

What are the 3 types of cell Junctions?

Answer 1

Gap Junctions
Anchoring Junctions
Tight Junctions

Question 2

What are the 4 main Transient cell communication ways?

Answer 2

Contact-Dependent
Paracrine
Synaptic
Endocrine

Question 3

What is Contact-Dependent signalling?

Answer 3

when a signal binds to a receptor on a interacting cell

Question 4

What is Endocrine signalling?

Answer 4

When the endocrine cell releases signals (hormones) that travel through the bloodstream and act on receptors of target cells at distant body sites

Question 5

What is Paracrine signalling?

Answer 5

Signals that are released by cells into extracellular fluid in their neighbourhood and acts locally

Question 6

What is Synaptic signalling?

Answer 6

Specific neurotransmitter signals at specialised junctions (synapses) between nerve cells

Question 7

What is Autocrine Signalling

Answer 7

Signals that act back on the secreting cell

Question 8

What are the 3 stages of cell signalling pathways?

Answer 8

Signal-Receptor Binding
Signal Transduction
Specific cell response

Question 9

What are receptors

Answer 9

proteins that recognise specific ligands (complementary shape) and mediate a response ( change in cell)

Question 10

What are the 3 main types of Membranes

Answer 10

• Ion channel-coupled receptors
• G Protein-coupled receptors (GPCRs)
• Enzyme-coupled receptors

Question 11

What 2 components do G Protein-linked receptors have similarities in structure with

Answer 11

Trans-membrane receptor
G protein