Lecture 7: case 2 Flashcards
What are our epithelial tumors
adenoma, carcinoma
what are our round cell tumors
lymphoma, TVT, MCT, plasma cell, histiocytic a (LYMPH)
what are our mesenchymal tumors
fibroma, sarcoma
how is neoplasia characterized
cell of origin and benign vs malignant
what cell shape is this and what type of tumors
polygonal- epithelial
spindle cells are associated with what tumors
mesenchymal
Cells that form clusters are associated with what tumors
epithelial
cells that are individualized or aggregated associated with what tumors
mesenchymal and round
what tumors produce ECM
mesenchymal
what is anisocytosis
variation in cell size between cells of same origin
what is anisokaryosis
variation in nuclear size between cells of same origin
what are the cytologic criteria for malignancy
- Anisocytosis
- Ansiokaryosis
- Multinucleation
- Less condensed chromatin
- Mitotic figures
- Nucleolar changes
What these and what mean
Normal Mitotic figures= bad
what these and what mean
abnormal mitotic figures= extra bad
what are the epithelial neoplastic features
- Polygonal cells
- Cell to cell junction
- Formation of clusters
benign epithelial tumor=
adenoma
malignant epithelial tumor=
carcinoma
what type of cells/tumor type
epithelial
what type of tumor is this and what are some examples
neuroendocrine
Insulinoma, pheochromocytoma, AGASACA
perianal adenomas aka
hepatoid tumors
what is classic signalment for perianal adenomas
Older, intact male
what type of tumor is this
perianal adenoma
what is atypical signalment for perianal adenoma and what should you evaluate
female spayed, male neutered
Evaluate adrenal or pituitary for tumors
from anal gland mass- what type of tumor and dx
Neuroendocrine tumor- apocrine gland adenocarcinoma of the anal sac
what paraneoplastic syndrome is associated with AGASACA
hypercalcemia—> tumor produces PTHrp
