Lecture 7 Flashcards

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1
Q

what information goes to each part of the brain from the eye

A

Contralateral– information from the nasal part of the retina crosses to the other side of the brain, such that the left visual field is seen by the right hemisphere and vice-versa

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2
Q

what does LGN stand for

A

Lateral Geniculate Nucleus

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3
Q

what is the LGN

A

where the information passes through to get to the brain (from vision)

there are 2, the left and the right

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4
Q

what are the Types of layes in the LGN

A

Magnocellular (1 and 2)

Parvocellular (3-6):

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5
Q

what is the Magnocellular (1 and 2) layer

A

Large cells, bottom two layers. Receive input from M ganglion cells. Respond best to large, fast-moving objects

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6
Q

what is the Parvocellular (3-6): layer

A

Smaller cells, top four layers. Receive input from P ganglion cells. Respond best to fine spatial details of stationary objects.

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7
Q

what are the Properties of the LGN:

A

Controlateral representation: left LGN recieves info from the right visual field and vice-versa.
Each LGN layer receives signal from one eye only.
Within each layer of the LGN, the neurons are arranged in a retinotopic map of the visual field. In other words, RGCs (receptive ganglion cells) with adjacent receptive fields connect to adjacent neurons in the LGN (AKA each spot in retina has a corresponding place in the LGN)

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8
Q

what is another name for the Primary visual cortex

A

striate cortex

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9
Q

what are Two important features of striate cortex

A

Retinotopic mapping

Cortical magnification

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10
Q

what is Cortical magnification

A

Dramatic scaling of information from different parts of visual field

Proportionally much more cortex devoted to processing the fovea than to processing the periphery (aka lots more space in the cortical magnification dedicated to the fovea than periphery)

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11
Q

what is Retinotopic mapping

A

each part in your visual field corresponds to a place in the straits cortex

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12
Q

Why sine gratings?

Any black-and-white image can be described in terms of a weighted combination of different : (there are 4 properties)

aka every image can be decomposed into what?

A

frequencies,
contrast,
phases, and
orientation

Low frequencies = broad outline
High frequencies = details

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13
Q

Retinal ganglion cells are sensitive to what

A

1) frequencies, 2) contrast, 3) phase, but not 4) orientation…

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14
Q

is it possible to detect the orientation fo an image with just one ganglion cell

A

no,

By combining information from SEVERAL retinal ganglion cells, it is possible to detect the orientation of lines.

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15
Q

what is the Tilt after-effect

A

We have different populations of neurons that specialise in certain frequencies and orientations.

Adaptation: Looking at a pattern of stripes for a certain time will “tire” the neurons and shift the balance in the opposite direction.
-> Note: this also implies that orientation is encoded by a population of neurons

(this is the example with the red dot embedded in the black and while lines)

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16
Q

define Sensation

A

Sensory receptors activated after receiving a specific input

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17
Q

define Perception

A

Interpretation of the sensory input

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18
Q

define Visual Sensation:

A

light activating photoreceptors (rods and cones)

in the retina

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19
Q

define Visual Perception

A

how the environment is consciously perceived after organization and interpretation of the retinal input

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20
Q

Visual Perception occurs at what level (where)

A

This occurs at the level of the cortex and involves both bottom-up and top-down processes including attention, context and preconceived ideas about the world.

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21
Q

how does sensation get translated into perception

A

via the visual pathway

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22
Q

how does the visual pathway/system work

A

From the retina, the visual information travels to the lateral geniculate nucleus (LGN) in the thalamus.

From the LGN, neurons project either to subcortical structures or to the visual cortex.

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23
Q

what is The subcortical structures for vision responsible for

A

are responsible for eye movements.

24
Q

what is The visual cortex responsible for

A

INTERPRETING the retinal input and giving us a visual experience

25
Q

The visual cortex is composed of what

A

the striate and the extrastriate areas

26
Q

From the LGN, visual information travels directly to where

A

the striate primary visual cortex (V1).

27
Q

From the LGN, visual information travels directly to the striate primary visual cortex (V1).

The visual information then travels into where

A

the extrastriate cortex that splits into two different streams.

28
Q

the extrastriate cortex is split into two different streams, what are they

A

the dorsal stream and the ventral stream

29
Q

what is the dorsal stream

A

motion processing

The ‘where’ or ‘how’ pathway

30
Q

what is The ventral stream =

A

object recognition

- The ‘what’ pathway

31
Q

V1 extracts what ind of information

A

V1 extracts very basic information from the visual input including the orientation of lines and direction of simple motion.

32
Q

The extrastriate areas extract what kind of information

A

more complex information in a hierarchical fashion

33
Q

what happens if you have Lesion in area MT (middle temporal)

A

Akinetopsia

34
Q

what is Akinetopsia

A

motion blindness

35
Q

what happens if there is a Lesion in Fusiform Face Area within the Infero-Temporal Cortex

A

Prosopagnosia

36
Q

what is Prosopagnosia

A

face blindness

37
Q

Lesions at any point in the two streams (dorsal or ventral) causes very specific deficits which are what

A

deficit in PERCEPTION not sensation– you can still see okay just cant interpret it

38
Q

what happens if there is a lesion before the V1 cortex (before the area where things are processed as being seen)

A

Cortical blindness

39
Q

what is Hemianopia

A

Cortical Blindness just another name

40
Q

what is ‘Cortical Blindness’ (CB)

A

severe loss of vision that follows damage to the primary visual cortex (V1) – affects the contralateral visual field of both eyes

41
Q

Cortical Blindness is most often caused by what

A

an ischemic stroke to the posterior cerebral artery

42
Q

how many stroke patients have permanent homonymous hemianopia (CB)

A

8-10%

43
Q

how does CB impact the patients life

A

affects the patients’ quality of life significantly, with many patients having difficulties reading, driving and navigating the world

44
Q

what are the treatments for CB

A

Currently, no treatments exist to recover vision loss after stroke

Most strategies used in rehabilitative centers used ‘compensatory mechanisms’ rather than recovery.

45
Q

If the eyes and the rest of the visual cortex are spared (in CB), is there a way vision could be rehabilitated ? Why do people think there might be?

A

Numerous studies have shown that CB subjects possess residual abilities in their blindfield, a phenomenon known as blindsight

46
Q

what is blindsight

A

cortically blind patients are able to discriminate or respond to stimuli without being aware of them.

47
Q

Blindsight differs from normal vision: in what 3 ways

A

1) It is largely unconscious
2) It is elicited most reliably by large stimuli
3) It seems to be restricted to coarse, flickering/moving stimuli

48
Q

does blindsight have functional utility

A

Although discrimination improves (in the experiment), there is no increase in awareness.

Blindsight has a limited functional utility

49
Q

Can cortically blind subjects be trained with other stimuli (that do not elicit blindsight)?

A

according to experiments: Yes

Visual recovery was attained with a wide variety of stimuli

Detection of shape, shape comparison, orientation discrimination, letter identification, motion direction discrimination

All stimuli were specially designed not to elicit blindsight

Stimuli are successful at reducing the size of the blindfield

Eye movements were controlled with eye trackers

Stimuli were presented fully in the blind field and light scattered was minimized

50
Q

How significant is the improvement? (with regard to the cortically blind subjects trained with other stimuli (that do not elicit blindsight))

A

The recovery is spatially limited and remains suboptimal

51
Q

How can we increase the clinical significance of recovered vision?
(for CB)

A

targeted visual plasticity

52
Q

what is Targeted Visual Plasticity

A

inducing plasticity in a targeted visual area through training

53
Q

the dorsal stream is primarily good for what

A

motion perception

54
Q

the ventral stream is primarily good for what

A

object recognition

55
Q

for the experiment regarding CB explain how improvements were made to allow for the patient (monkey) to use other parts of the dorsal stream to compensate

A

After training with a simple stimulus, deactivating area MT does not affect motion perception of the simple stimulus significantly

After training with a complex stimulus, deactivating area MT does affect motion perception of the complex stimulus significantly

After training with a complex stimulus, deactivating area MT ALSO affects motion perception of the simple stimulus significantly