Lecture 7 Flashcards
Are all goblet cells glands?
No, only the ones in the respiratory and intestine that secrete onto a surface
Where are the parotid glands located?
Below and in front of the ear and the side of the mouth
How are parotid glands controlled?
Parasympathetically, dry mouth when stressed.
Enclosed in a fibrous capsule, swelling of the gland therefore produces pain in parotitis
What are the secretions of the various glands like?
Parotid- totally serous
Submandibular- mostly serous partly mucus
Sublingual- almost all mucus
What is the largest exocrine gland?
The liver
What is the appearance of the liver in cirrhosis?
Hard
How does that hepatic portal vein work?
Artery brings blood to GI tract and breaks into capillaries. Then leaves and forms hepatic portal vein to liver where it breaks into capillaries again.
How does blood get to the liver?
75% through the hepatic portal vein and 25% directly from the heart through the hepatic artery. These come together then and travel through the sinusoids.
What is a sinusoid?
An irregularly shaped tube through which blood passes.
What is a liver lobule?
Building block of liver matter consisting of a portal triad, hepatocytes and a central vein. It is hexagonal nd six sided
What is a liver acinus?
Functional unit of the liver. A portal triad and surrounding cells.
What are kupffer cells?
Specialised macrophages that form part of the sinusoidal lining. If spleen removed these cells take over role of removing aged erythrocytes.
Why are stellate cells clinically important?
They store vitamin A. In liver cirrhosis they lose the ability to store vitamin A and become myofibroblasts which lay down collagen and cause liver fibrosis
Liver storage function?
Lipid soluble vitamins like A, D, B12 and K
Glycogen
Copper
Iron
Liver anabolism function?
Plasma proteins like albumin
Enzymes
Amino acids
Lipoproteins
