Lecture 6 - Neuroimaging methods Flashcards
studying pairwise connections from connected neurons looks at which 2 types of characterisation?
physiological and anatomical
anterograde tracing traces axonal projections from ….. to …….
source (soma) to termination (synapse)
retrograde tracing traces from …… to …….
termination to source
name some methods for measuring activity in the CNS
EEG, MEG, ECoG, LFP, fMRI, single neuron recordings
in stage 4 in sleep which two types of activity would we expect to see the most on an EEG?
theta and delta activity
in an awake patient which type of activity would we expect to see on an EEG?
gamma
an ECoG increases the …… resolution not the temporal. It is done on patients with which condition? where are electrodes placed?
spatial, epilepsy, directly on exposed surface of the brain (cortex)
LFP (local field potentials) can record from different …. levels in the brain
cortical
how many neurons are typically compared in single neuron activity measuring?
1-3
name a method for perturbing the CNS which is external and uses a visual evoked potential?
EEG
name a method for perturbing the CNS which is peripheral and non-invasive and can use an electrical or mechanical stimulation
EEG
name a method for perturbing the CNS which is cortical and non-invasive, helpfuk for seeing motor systems moving
TMS
name a method for perturbing the CNS which is used to estimate corticospinal tract excitability
MEP
give the types of legions with an example for each which can be used as methods for perturbing the CNS in neuroimagine
mechanical (heat)
chemical (60HDA)
vasoconstriction (endothelin 1 )
magnetic (rTMS)
