Lecture 17 - Spinal circuits Flashcards
what is decussation regarding the descending pathways?
the right and left corticospinal tracts cross over at the medulla
true or false, the motor system is hierarchical?
true
locomotion comes from what type of generators, what type of feeback and what type of input?
central pattern, sensory, descending
which 2 genes control the development of dorsal/posterior areas in spinal circuit development?
wnt, bmp
which gene controls the development of ventral/anterior areas in spinal circuit development?
shh
in early development which 2 things are active before the sensory reflex is complete?
motorneurons and central pattern generators
which type of interneurons do renshaw cells inhibit for extension?
1a
VI interneurons use which 2 neurotransmitters to allow alternating activity between flexor and extensor motoneurons?
GABA and gylcine
what do gamma sensory fibres detect?
touch, pain, heat, vibration
what do C sensory fibres detect?
pain, heat
which 3 types of sensory fibres are heavily myelinated and which are lightly myelinated?
alpha, beta, delta heavily, gamma lightly
the stretch reflex is …..synaptic but the flexor reflex is …..synaptic
mono, multi
give an example of the flexor and crossed extensor reflex?
stepping on something sharp and planting the other foot on the ground to move the harmed foot up and away promoting extension
in the flexor and crossed extensor reflex, what inhibits flexor motion with interneurons?
CPGs
which type of neurons work the arms and the legs at the same time? which 2 regions of the spinal cord do they communicate between?
long propriospinal neurons, cervical and lumbar