Lecture 6 - Healthy ageing

Question 1

in the epidemiologic transition, disease in more developed countries change from…… to …….

Answer 1

communicable to life style related/chronic diseases

Question 2

for healthy ageing, how mnay activity/mobility measures are there? how many performance measures?

Answer 2

13 mobility, 5 performance

Question 3

what does biological age use to predict age? give examples

Answer 3

using biological parameters to predict age - e.g telomere length, Il-6 or serum albumin levels

Question 4

define incidence of disease

Answer 4

new cases of disease per 1000 people

Question 5

define prevalence of disease

Answer 5

amount of disease in a population % (new + existing cases)

Question 6

name 5 diseases in which the prevalance and incidence continue to increase as people get older

Answer 6

dementia, stroke, diabetes, arthritis, cancer

Question 7

name the 5 I’s (ageing giants)

Answer 7

immobility, incompetence, incontinence, impaired homeostasis, iatrogenic disorder

Question 8

does muscle strength and CSA decrease with age? what is a biomarker for it?

Answer 8

yes both do, grip strength test

Question 9

what is sarcopenia the loss of in terms of muscle? 3 things

Answer 9

strength, mass, function