Lecture 6- Gastrointestinal Flashcards

1
Q

4 digestive functions of saliva

A

taste

lubricant

initiates digestion of starch

initiates digestion of fat

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2
Q

major source of amylase?

A

parotid gland

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3
Q

the parotid is a … gland that produces a …. secretion

A

serous

watery

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4
Q

Where is the parotid (stensens) duct?

A

opposite upper 2nd molar

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5
Q

the submandibular (whartons) duct opens…

A

beneath the base of the tongue

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6
Q

what kind of secretions come from the submandibular gland?

A

mixed; serous and mucous

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7
Q

T/F the submandibular gland is active at rest

A

true

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8
Q

secretions from the submandibular gland include…

A

water, electrolytes, mucin

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9
Q

amylase breaks down?

A

carbs

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10
Q

when does carbohydrate digestion begin?

A

in the mouth

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11
Q

the sublingual gland produces mostly … and ducts are found on …

A

mucous

anterior floor

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12
Q

what are the 5 minor salivary glands that contribute to 5-10% of total saliva and harbor lymphocytes

A
labial
palatine
buccal
lingual (von ebners)
sublingual mucosae
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13
Q

… glands have a complex secretory composition that facilitates contact with taste buds and rinses ducts of circumvallate and foliate papillae

A

von ebners

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14
Q

T/F von ebners glands are involved in taste

A

true

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15
Q

von ebners glands secrete …. which initiates …. digestion

A

lingual lipase

fatty acid

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16
Q

T/F fatty acid and carb digestion begins in the mouth

A

true

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17
Q

pH highly buffered … to…

A

6.7 to 7.4

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18
Q

what is the most important mechanism in salivary fluid secretion

A

sodium potassium ATPase pump

19
Q

in salivary fluid secretion, intracellular Na is kept … , intracellular K is kept … and intracellular Cl is kept …

A

low

high

high

20
Q

In unstimulated cells, calcium levels are … and calcium activated K and Cl channels are closed

A

low

21
Q

upon stimulation, calcium … the Cl and K channels

A

opens

22
Q

Na leaks through tight junctions to follow…

A

Cl

23
Q

The acini are where … secretion takes place and it is H2O …

A

primary

permeable

24
Q

The duct is where … modification takes place and it it H2O …

A

secondary

impermeable

25
Q

what is the most abundant protein in saliva?

A

mucin

26
Q

mucin is predominately produced by … and … glands

A

sublingual and submandibular

27
Q

mucin is a …. rich protein

A

carbohydrate

28
Q

amylase is predominately produced by the … gland

A

parotid

29
Q

amylase is packaged in … granules

A

zymogen

30
Q

… initiates the breakdown of starch

A

amylase

31
Q

T/F mucin is produced by the parotid gland

A

false

32
Q

… is a digestive protein that is produced by von ebners glands

A

lingual lipase

33
Q

what are 3 immune-associated proteins in the saliva?

A

muramidase (lyse muramic acid in cell wall of bacteria)

immunoglobulins

lactoferrin (binds iron)

34
Q

T/F calcium binding proteins and growth factors are present in the saliva

A

true

35
Q

T/F parasympathetic and sympathetic nervous systems have a role in the secretio of saliva

A

true

36
Q

In parasympathetic innervation, the facial (7) nerve innervates which glands?

A

glands of palate and nose

sublingual

submandibular

37
Q

In parasympathetic innervation, the glossopharyngeal nerve (9) innervates which glands?

A

parotid

lingual

38
Q

what components of saliva secretion are innervated by the autonomic nervous system?

A

acinar cells

ductal cells

blood vessels

myoepithelial cells

39
Q

the parasympathetic system produces more of a …. saliva and the sympathetic system produces more of a …. saliva

A

watery

viscous

40
Q

the key neurotransmitter in the parasympathetic system for salivation is …

A

acetylcholine

41
Q

the key neurotransmitter in the sympathetic system for salivation is …

A

norepinephrine

42
Q

mechanoreceptors in the … and … stimulate saliva production. they synapse in the … and … nucleus

A

PDL
tastebuds

trigeminal
solitary

43
Q

… stimulation greatly enhances protein secretion (especially through …. receptors). this is mediated through …. signaling

A

sympathetic

beta-adrenergic

GPCR

44
Q

what autoimmune disorder can cause xerostomia

A

sjorgrens syndrome