Lecture 6 Flashcards
DoHaD
Environmental factors (nutrition,
chemical exposures, etc.) during prenatal
and postnatal development alter
susceptibility to adult chronic diseases
by influencing developmental plasticity, originally known as Barker’s Hypothesis
epigenetics
“The branch of biology which studies the
interactions of genes and their environment that
bring the phenotype into being
genome
complete set of DNA in a cell
epigenome
chemical compounds that modify the genome
DNA methylation
the process by which a methyl group is added to DNA regulating gene expression and contributing to disease
histone modifications
modification(s) directly influencing the overall structure of chromatin, either over short or long distances