Lecture 6 Flashcards

1
Q

Buffers

A

solutions that resist pH changes
Act by neutralizing added acid or base
Made by preparing a solution of a weak acid/base and the salt of its conjugate acid/base

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2
Q

Henderson-Hasselbalch Equation

A

Used to calculate pH of buffer solution

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3
Q

In the Henderson-Hasselbalch Equation, if A and B are equal…

A

pH=pKa
This is a buffer equally prepared to neutralize acids and bases

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4
Q

H+/OH- catalyze what?

A

hydrolysis/condensation reactions

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5
Q

pH affects?

A

the charge on an enzyme
its shape
ability to function

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6
Q

Forms of dissolved CO2 steps

A
  1. dissolved CO2 forms carbonic acid H2CO3
  2. Carbonic acid then forms the bicarbonate ion HCO3-
  3. Bicarbonate can go on to form carbonate ion CO32-
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7
Q

Removal of CO2 by the lungs does what?

A

shifts this reaction to the left (by Le Chateliers Principle) reducing carbonic acid and raising pH

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8
Q

Respiratory Acidosis/ Alkalosis

A

Acidosis /alkalosis due to breathing problems (removal of CO2)

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9
Q

Metabolic Acidosis or Alkalosis

A

Acidosis or alkalosis due to metabolic problems (diarrhea/vomiting, ketoacidosis, or kidneys problems)

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10
Q

pH Compensation

A

If one of the two modes of pH regulation fails, the other will try to Compensate

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11
Q

Partial compensation

A

pH is not returned to the reference range: 7.35-7.45

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12
Q

What is the normal body pH range?

A

7.35-7.45

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13
Q

Full compensation

A

pH is returned to the reference range: 7.35-7.45

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14
Q

Vomiting

A

Vomiting removes stomach acid
Raises pH, metabolic alkalosis

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15
Q

Diarrhea

A

causes loss of bicarbonate
Lowers ph, metabolic acidosis

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16
Q

Respiratory acidosis

A

Reduced CO2elimination

17
Q

Respiratory alkalosis

A

increase CO2 elimination