Lecture 6 Flashcards
Passive Transport
Originally told it doesn’t need energy to work, but it needs a little energy to work. It uses gradient energy. ex: aquaporin, glyceroporin
Active Transport
Requires energy. To get anything in or out of the cell. ATP is primary energy and PMF is secondary energy
Primary Active Transport
ATP is the primary energy used in active transport. It is an ATP binding cassette (ABC)
ABC ATPase
ABC transporters are transmembrane proteins that utilize the energy of ATP hydrolysis to carry out certain biological processes including translocation of various substrates across membranes and non-transport-related processes such as translation of RNA and DNA repair
Secondary Active Trasnport
Uses PMF for energy. Uniports use electrical potential. major facilitator superfamily uses H+ gradient
MFS Transporters
Major Facilitator Superfamily. Proteins use energy from gradient of one ion to more another ion or uncharged solute against its gradient
Uniport
Uses electrical potential like a magnet to put charged ions into or out of the cell
Symport
Ions passing through in the same direction
Antiport
Ions passing through in different directions
Rocker-switch mechanism
Is believed to be how gated channels open and close. The components literally rock
Phosphotransferase System
uses a phosphate relay to transport glucose. glu-6-P does not diffuse back out of the cell
Type I secretory system
Can cross the membrane in one step to get proteins out of the cell
Drug efflux pump
Mechanism responsible for moving out of toxic substances and antibiotics outside the cell
Type III secretory system
Can cross the membrane in one step to get proteins out of the cell. But bacterium has to contact the host cell first
Needle complex
It pushed the protein across the membrane
