Lecture 5: Electrical Events of the Heart Flashcards
what is the basis of the electrocardiogram?
body = volume conductor
when cardiac muscle cells depolarise, extracellular current between resting and depot causes potential difference that can be measured at the body surface
in what direction does current flow?
from -ve to +ve
what a cell depolarises what is the net charge on the OUTSIDE?
-ve
what are einthovens 5 hypotheis’
- heart is located at the centre of a homogenous volume conductor
- attachment of arms and legs to trunk = equidistant
- limbs behave as linear conductors to trunk
- electrodes placed on limb = located at apices of equilateral triangle
- differences in potential recorded between electrodes represent projection of vector forces
what are the three main ECG leads?
Lead 1: right arm -ve, left arm +ve
Lead 2: right arm -ve, left leg +ve
lead 3: left leg -ve, right arm +ve
which lead is the most accurate vector analysis?
lead 2
what are the limitations to einthovens hypothesis in regards to quadrupeds?
- limb arrangement is much less like an equilateral triangle
- anatomical attachment of forelimbs to body is different
- moving limbs alter amplitude and direction
describe the general features of an ECG wave
P wave = depol of atria
QRS complex = ventricular depot
T wave = ventricular repol
(can’t see atrial repol, hidden behind QRS complex)
What type of contraction is the P-R, and S-T segment?
iso-electric
what is the P-R interval?
the delay between atrial and ventricular depol due to eh delay in the AV node
what is the S-T segment?
plateau of ventricular muscle action potential
Why is the T wave not inverted?
endocardial cells depolarise first, then the epicardial cells epicardial cells (on the outside) REPOLARISE before the endocardial cells ie/ tissue that depol last in the tissue are the first to repol
what can change the mean electrical axis of the heart?
change in position of the heart eg/ mass in the thorax
increase in mass in one of the ventricles
what is an arrhythmia?
an alteration in rate or rhythm
what is bradycardia?
slowing of heart rate