Haemangiosarcoma, haemabdomen

Question 1

What is the reference range for PCV of a dog

Answer 1

35-55

Question 2

What is the general blood pressure of a dog

Answer 2

130/80

Question 3

Murphy’s systolic pressure was 40mmHg, what might you expect his BP to be at the arterial end of a capillary? Why is this important?

Answer 3

~10mmHg, he’ll have very poor perfusion of tissues, so they will start anaerobically respiring.

V low hydrostatic pressure will mean vessels will start reabsorbing water from eCF!

RAAS will be activated

Inc RESP & collapse

Question 4

Why would administration of hartmann’s exacerbate Murphy’s condition?

Answer 4

Would cause further haemodiltution, further decreasing plasma oncotic pressure

Question 5

How does Murphy’s poor venous return affect his heart function

Answer 5

Reduced BP & preload, thus reduced SV and CO

Question 6

Why is RAAS activated?

Answer 6

Dec BP, Dec capillary hydrostatic pressure –> kidneys will conserve Na + H20 (will further dilute PCV :( )

Question 7

Murphy is treated with fresh frozen plasma and cells, how will this change his cardiac function?

Answer 7

INC blood volume, INC venous return, INC EDV (preload), INC adequate stretch of heart to INC force of contraction thus INC SV, CO and hence systolic pressure (BP)