Lecture 4C: Single Subject Designs Flashcards

1
Q

What continuum of research includes single-subject design?

A

Descriptive, Exploratory, Experimental.

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2
Q

What is a key characteristic of single-subject designs?

A

One subject.

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3
Q

In what setting do single-subject designs usually take place?

A

Clinical setting.

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4
Q

What does a single-subject design compare?

A
  • Effects of one treatment & control
  • Effects of different treatments.
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5
Q

What can we conclude from single-subject designs?

A

Effects of treatment based on the response of a single patient under controlled conditions.

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6
Q

What are the basic requirements for single-subject designs?

A
  • Baseline & treatment phases
  • Repeated measures (at least 3-4 per phase)
  • A target behavior that is observable, quantifiable, and a valid indicator of treatment effectiveness.
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7
Q

What are the two things to look for in baseline data?

A
  • Stability
  • Trend/slope.
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8
Q

What does stability in baseline data refer to?

A

Consistency of response over time.

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9
Q

What does trend/slope in baseline data indicate?

A

The rate of change in behavior.

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10
Q

What is the structure of an A-B Design?

A

Baseline Phase (A) followed by Treatment Phase (B).

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11
Q

What is the main advantage of an A-B-A-B Design?

A

Stronger evidence of a treatment effect if the effect is replicated during two separate intervention periods.

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12
Q

What is a disadvantage of the A-B-A-B Design?

A

Carry-over effect.

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13
Q

What does the A-B-A-C Design compare?

A

The effects of two different treatments.

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14
Q

What is a disadvantage of the A-B-A-C Design?

A

Previous effects of treatment B may affect the response to treatment C.

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15
Q

What are the advantages of single-subject designs?

A
  • Easily employed in clinical setting
  • One subject only: easy to recruit
  • Good source of data for the formation of hypotheses
  • Provides pilot data for future RCT.
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16
Q

What are the disadvantages of single-subject designs?

A
  • History effects
  • Not representative of study population
  • Limited generalizability
  • Difficult to apply to subjects with acute conditions.
17
Q

Fill in the blank: A-B design is commonly used to assess the effect of a new medication on pain in a single subject with rheumatoid arthritis using a _______.

A

Visual Analog Scale.

18
Q

What is the most serious threat to internal validity in a single-subject A-B design?