Lecture 4: Introduction to GENERAL osteology Flashcards
What are the 3 main types of bone cells and explain their purpose
1) Osteoblast: (building/immature bone cell)
2) Osteocyte: (fully mature/functional bone cell=does the “maintenance”
3) Osteoclast: breakdown of bone (destroy harmful cells, release minerals from bone, make room for new bone cells)
What are the 7 main features of long bones?
Diaphysis: shaft
Epiphysis: proximal and distal ends
Metaphyses: contains epipheseal plate (which is originally cartilage which allows it to grow but eventally calcifies into a plate)
Articular Cartilage: Around the edges that articulate
Periosteum: Covers the outside of bone (except where articular cartilage is)
Medular cavity: Hollow to make bones lighter and to make room for cells
Endosteum”: lines medular cavity
BE ABLE TO LABEL AND LONG BONE WITH ALL THE FEATURES (diaphyses etc)
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Explain compact bone and where can you find it
Observed at the surface of a bone along the edges and makes up most of the diaphysis of long bones
Looks dense but is pourous and offers protection and support
- Offers protection and support
- Resistant to stresses caused by weight and movement
What is a big reason your bones are resistant to stresses caused by weight and movement
COMPACT BONE
What are the components of COMPACT BONE tisse?
Osteons Osteonic canal Concentric lamellae Lacunae Caniculae Intersticial lamellae Interosteonic canals Circumferential lamellae Sharpeys fibers
BE ABLE TO LABEL ALL THE COMPANETS OF COMPACT BONE TISSUE
look at slides for diagram
What is the osteon
Structural unit of the compact bone (tube withing a tube)
What is the osteonic canal?
In the center of osteons to provide blood supply (they are the vertical canals)
What are the concentric lamellae?
RINGS
You will find osteocytes inside the osteon maintaining equilibrium
What is the lacunae
Space between the lamella (lake/surround around the osteocytes
What is the canniculae
“appendages” that connect each osteocyte
What are the intersticial lamellae
gaps between osteocytes
what are the interosteonic canals and another name for them
In between osteons (they are the horizontal canals)
volkmann canals
What are the circumferential lamellae
Follows around the circumference of the bone
What are perforatiing (sharpeys fibers)
They anchor the perioosteum to the bone surface and they make it so the bone can adapt to many forces
Does the Periosteum completely cover the long bones?
NO it covers most (the diaphyses) but does not surround bone ends at articular cartialge
What are the 2 layers of Periosteum
Fibrous OUTER LAYER
and Osteogenic inner layer (sharpeys fibers)
True or false: The spongy bone tissue contains osteons?
FALSE
What are 2 other names for spongy tissue bone?
Trabecular and cancellous
Where is spongy tissue found?
interior of the bone, protected by covering of compact bone
What are the 4 main components of spongy tissue>
Concentric lamellae
Osteocytes
Lacunae
Canaliculi
What are the 2 main differences between compact bone tissue and spongy bone tissue
SPONGY BONE DOES NOT CONTAIN OSTEONS
spongy bone is arranged in an irregular fashion
What are the spaces between the trabeculae filled with?
RED BONE MARROW
YELLOW BONE MARROW
What does red bone and yellow bone marrow produce?
RED: RED BLOOC CELL PRODUCTION
YELLOW: ADIPOSE TISSUE
What are the 4 main arteries for the bones?
Periosteal arteries: supply periostum and outer part of compact bone
Nutrient artery: enters center of disaphyses
metphyseal arteries: in the middle (arteries around joint)
epiphyseal arteries: outer ends
be able to label blood supply diagram
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What are the 4 stages to bone formation?
1) Initial formation in embryo and fetus
2) General growth through infancy, childhood, and early adulthood
3) Bone remodeling through life
4) Repair (from fractures) through life
What are the 2 types of ossification (bone formation) and what bones form from which?
1) Intramembranous ossification (flat bones, skull, facial bones, mandible)
2) Endochondral ossification (most other bones)
Be able to label compact/spongy bone structure
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What are the 4 steps to INTRAMEMBRANOUS ossification (flat bones, skull)
1) Development of the ossification center
2) Calcification
3) Formation of trabeculae
4) Development of the periosteum
What is the main difference between Intramembranous and endochondrol ossification?
intramembranous has NO CARTILAGE MODEL
True or false and explain: Flat bones have a lot of hollow spaces
FALSE, flat bones are completely occupied by tissue
What are the 6 steps of endochondrol ossification
1) development of the cartilage model
2) growth of cartilage model
3) dev of primary ossification center (beings in the diaphysis)
4) Dev of the medullary cavity (hollow inside)
5) dev of secondary ossification centers (occur in the epiphyses of the bone)
6) Formation of articular cartilage (around bone articualting surfaces) and the epihyseal growth plate
Where does the primary ossification center develop
Where do the secondary ossification centers develop
POC= begins in diaphysis
SOC=beings in epiphyses
True or false? The epiphyseal is the only place for length growth in the bone?
true
What are the 4 zones in the epiphyseal plate for growth?
- Zone of reserve/resting cartilage
- Zone of proliferating cartilage
- Zone of hypertrophic cartilage
- Zone of calcified cartilage
- Zone of calcified cartilage
- Dead chondrocytes because extracellular matrix has calcified
- Osteoclasts dissolve calcified cartilage, then osteoblasts and capillaries invade area
- Osteoblasts lay down bone extracellular matrix, process of endochondral ossification, “new diaphysis formed as a result
Be able to label the zones of an epiphyseal plate
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