Lecture 4 Flashcards

1
Q

gradient of electrochemical potential usually for an ion that can move across a membrane; consists of electrical potential and chemical concentration across a membrane

A

electrochemical gradient

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2
Q

difference in electric potential between the interior and exterior of a biological cell

A

membrane potential

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3
Q

formula for calculating the membrane potential based on internal and exterior concentrations of ion distributed differentially across a bilayer

A

nernst equation

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4
Q

helps maintain the resting potential and regulate cellular volume; responsible for about 1/5 of the cell’s energy energy expenditure except neurons (2/3 of neuron’s energy expenditure)

A

Na K ATPase

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5
Q

structure that permits a neuron nerve cell to pass an electrical or chemical signal to another cell

A

synapse

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6
Q

high intracellular concentration, low extracellular concentration

A

Potassium

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7
Q

low intracellular concentration, high extracellular concentration

A

Sodium

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8
Q

Movement of Na and K in NaK ATPase

A

3 Na Out, 2 K in

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9
Q

Ion channels show ion selectivity T/F

A

True

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10
Q

ion channels are continuously open T/F

A

False

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11
Q

pores show ion selectivity T/F

A

False

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12
Q

Types of channeling gating

A

voltage, ligand (intra and extracellular), and stress

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13
Q

action potentials are unidirectional T/F

A

True

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14
Q

membrane depolarization is caused by which ion

A

Na+

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15
Q

membrane repolarizes because of which ion

A

K+

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16
Q

caused by mutations in CFTR gene which is a chloride channel

A

cystic fibrosis

17
Q

superfamily of integral membrane proteins responsible for ATP-powered translocation of molecules like sugars, aa, lipids, etc

A

ATP-Binding Cassette (ABC) Transporters

18
Q

What are the domains of ABC transporters?

A

2 hydrophobic and 2 ATP-binding

19
Q

cycle that moves iron in and out of the cell

A

Transferrin cycle