Lecture 30: Immune Evolution Flashcards
1
Q
Do invertebrates have adaptive immunity ?
A
No only innate
2
Q
Why study evolution of immune system ?
A
- Conserved elements important
- Some elements more effective in some species
- Discovery of new ways of regulating human immune mechanisms
- Important differences in other species may be important to humans
3
Q
What is evolution ?
A
Emergence of new species due to inherite advantageous mutations
4
Q
What is molecular evolution composed of ?
A
- Genome duplication
- Chromosome duplication
- Gene duplication
- Time
5
Q
What are the methods of bacterial defence ?
A
- Change pH
- Generate oxygen
- Scavenge nutrients
- Kill enemy
6
Q
What are bacteriocins ?
A
Bacterial anti-bacterial mechanisms
7
Q
What type of peptides in antimicrobial peptides ?
A
Short peptides
8
Q
What are antimicrobial peptides encoded as ?
A
Inactive precursor proteins
9
Q
What are antimicrobial peptides expressed by ?
A
Neutrophils and epithelial cells