Lecture 3: Thermoregulation Flashcards

1
Q

What parts of the body change temperature the most rapidly?

A

Feet, then hands, then skin

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2
Q

About how much does the core temperature change throughout the day?

A

1-2 degrees

Lowest at 6 am

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3
Q

What measures core temperature?

A

Thermal Receptors

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4
Q

What are the cutaneous thermoreceptors most sensitive to?

A

Cold (10x as much as warm)

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5
Q

What information do the visceral thermoreceptors transmit?

A

Threats from ingested food that may change body temperature => hypothalamus

  • Example: ice cream
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6
Q

Where are the thermoreceptors of the brain located?

A

Pre-optic and superoptic region of hypothalamus

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7
Q

What are the thermoreceptors in the brain most sensitive to?

A

Heat (3x as much as cold)

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8
Q

What structure determines the set body temperature?

A

Hypothalamus

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9
Q

What happens to the core temperature when you sleep and exercise?

A
  • Sleep: set point decreases
  • Exercise: set point icnreases
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10
Q

What does the posterior region of hypothalamus respond to?

A

Responds to cold by producing heat

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11
Q

What does the anterior region of the hypothalamus respond to?

A

Responds to heat by lowering heat

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12
Q

Why do babies need more adipose tissue?

A

Babies have higher surface area in proportion to size and will lose heat faster than adults

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13
Q

What part of the hypothalamus is responsible for shivering?

A

Dorsomedial posterior hypothalamus => increase motor neuron excitation

You are cold and trying to produce heat

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14
Q

What division of the autonomic nervous system is involved in heat production?

A

Sympathetic Nervous System

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15
Q

In non-shivering thermogenesis, what hormone is released in response to cold?

A

Thyroxin-Releasing hormone => Thyroxin

Epinephrine

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16
Q

What activates hydrolysis of ATP in brown fat?

A

Sympathetic fibers => Epinephrine

17
Q

What are the two kids of evaporative heat loss?

A

Insensible (respiratory)

Sweating (controlled)

18
Q

What is convection?

A

Movement of molecules away from contact

Air Heating and Rising

19
Q

What is conduction?

A

Transfer of heat between objects in physical contact with one another

20
Q

What is radiation?

A

Transfer of heat between 2 objects that are not in physical contact

21
Q

What is the innervation to the sweat glands?
Activated by what NT?

A

Sympathetic cholinergic innervation

NT: Acetylcholine - binds mAChR

22
Q

If there is a low flow rate of sweat, what is the sodium concentration?

A

High (couldn’t follow water)

23
Q

If there is a high flow rate of sweat, what is the sodium concentration?

A

Low (no time to reabsorb water)

24
Q

What happens to the body when there is a fever?

A

Set Point increases and will be greater than body temperature

  • Endotoxins and Prostaglandin released