Lecture 3 - Cells and Tissues of the Immune System 2 Flashcards

1
Q

Four paradigms of the immune system

A

1) Immune recognition
2) Immune effector function
3) Immune regulation
4) Immune memory

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2
Q

Is there more eukaryotic or prokaryotic DNA in a human body?

A

Prokaryotic

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3
Q

Is inside the mouth inside the body?

A

No

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4
Q

Definition of ‘inside the body’

A

When the epithelial barrier has been surpassed

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5
Q

Why is a foetus of interest to immunologists?

A

Despite the foetus having a different genetic code to the mother, the foetus is not attacked by the immune system in implantation and growth

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6
Q

Method of improving IVF outcomes

A

Injure epithelium of womb

Inflammation might be important for pregnancy

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7
Q
Cardinal signs of inflammation
1)
2)
3)
4)
5)
A

1) Dolor
2) Calor
3) Rubor
4) Tumor
5) Function laesia

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8
Q

What is cognate interaction?

A

Interaction between antigen-presenting cell and naive T cell bearing receptor for presented antigen

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9
Q

Structure of naive T cell Vs activated T cell

A

Naive T cell is mostly nucleus

Activated T cell has more cytoplasm, denser nucleus

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10
Q

Immunopathology

A

Damage to body from immune response

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11
Q

Example of immunopathology

A

Hepatitis
Hepatitis doesn’t damage host hepatocytes
CD8+ response to hepatitis infection is what causes damage

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12
Q

Innate immune effector mechanisms
1)
2)
3)

A

1) Phagocytosis
2) Microbicidal agents
3) Complement

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13
Q

How are the innate and adaptive immune systems bridged?

A

1) Dendritic cell phagocytoses antigen
2) Travels to local lymph node
3) Presents to naive T cells

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14
Q

Antibody functions
1)
2)
3)

A

1) Neutralisation of toxins
2) Opsonisation
3) Complement activation

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15
Q

Stages of T cell immune response
1)
2)
3)

A

1) Expansion
2) Contraction
3) Memory

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16
Q

What occurs during T cell contraction?

A

Dying off of clonally-expanded T cells

17
Q

What is opsonisation?

A

Marking of objects for phagocytosis