lecture 3 Flashcards
What are the main hormones of the gastrointestinal tract (GIT)?
Gastrin, secretin, cholecystokinin (CCK), motilin, and gastric inhibitory peptide (GIP)
What is the role of gastrin?
Gastrin stimulates the secretion of gastric acid (HCl) from parietal cells in the stomach.
What is the role of secretin in digestion?
Secretin stimulates the pancreas to release bicarbonate, which neutralizes acidic chyme in the duodenum.
What does cholecystokinin (CCK) do in the digestive process?
CCK stimulates the release of bile from the gallbladder and pancreatic enzymes for fat and protein digestion.
What cells in the pancreas secrete insulin?
Beta cells in the islets of Langerhans
What is the function of insulin?
Insulin lowers blood glucose by promoting glucose uptake by cells and glycogen storage.
What cells in the pancreas secrete glucagon?
Alpha cells in the islets of Langerhans
What is the role of glucagon in the body?
Glucagon raises blood glucose levels by promoting glycogen breakdown in the liver.
What are the main digestive enzymes secreted by the pancreas?
Amylase (carbohydrates), lipase (fats), and proteases like trypsin and chymotrypsin (proteins)
What is the function of pancreatic lipase?
Lipase breaks down fats into fatty acids and glycerol for absorption in the small intestine.
How do the pancreatic ducts and biliary ducts interact?
The pancreatic duct and the common bile duct join at the ampulla of Vater, releasing their contents into the duodenum via the sphincter of Oddi.
What is Type 1 diabetes mellitus?
An autoimmune condition where the body attacks insulin-producing beta cells in the pancreas, leading to insulin deficiency.
What is Type 2 diabetes mellitus?
A metabolic disorder characterized by insulin resistance, where the body’s cells do not respond properly to insulin, often associated with obesity.
What is gestational diabetes?
A form of diabetes that occurs during pregnancy, where the body cannot produce enough insulin to meet increased demands.
What are the three phases of digestion?
The cephalic phase, gastric phase, and intestinal phase