LECTURE 27: REPRODUCTION

Question 1

Combined oral contraceptive pill

Answer 1

Contains pepsin and oestrogen-prevent ovulation by suppressing maturation of follicles

Progestin suppresses gnrh release and lh release, oestrogen inhibits lh and fsh

Question 2

Progestin only pill

Answer 2

• Lowdose makes cervix mucosa thicker
• intermediate - mucosa thickens and ovulation surpassed
• Mpa injection - same

Question 3

Pre-eclampsia and treatment

Answer 3

• Hypertensive disorder
• prevention= calcium supplement
• treatment = calcium channel blockers, lebatolol

Question 4

What anti-hypertensive drugs are contraindicated for pre-eclampsia

Answer 4

Ace inhibitors and angiotensin receptor two inhibitor

Question 5

Eclampsia

Answer 5

Onset of seizures

Question 6

Does eclampsia use same drugs

Answer 6

yes

Question 7

Drugs used in pregnancy

Answer 7

For pain-opiods, epidural
Uterus- oxytocin
Induce labour- oxytocin and misoprostol

Question 8

Abortion

Answer 8

Termination of pregnancy

Question 9

Medically induced by the abortion two drugs:

Answer 9

Misoprostol and mifepristone

Question 10

Misopristol

Answer 10

Inhibits progesterone signalling → thins endometrium and detaches embryo → dilates cervix and induces contractions toexpel contents.

Question 11

Mifepristone

Answer 11

Competitively blocks progesterone receptor in presence of progesterone, or acts p as apartial agonist in absense

Question 12

Magnesium sulphate importance

Answer 12

Prevents conversion of pre-eclampsia to eclampsia and prevents seizures