Lecture 23: Effector Mechanisms in T-cell Mediated Response Flashcards
Recall the following timeline of immune response.
Pathogen clearance requires _______________
Recall the two major subsets of conventional T cells.
Recall the principle effector mechanisms of activated T cells.
Dendritic cells are ___________.
Initiation of T cell responses by ______________.
Describe the process of T cell priming.
T cell extravasation controlled by _____________
Recall T cell migration to skin.
Recall T cell migration to gut mucosa.
Recall the concept of tissue-specific migration imprinting in lymph nodes.
Recall the concept of T cell functional polarisation.
T cell responses are tailored to distinct pathogens
Recall the differentiation of Th1 effector T cells.
Recall the effector functions of Th1 cells.
Recall the differentiation of Th17 cells.
Recall the effector functions of Th17 cells.
Recall the differentiation of Th2 effector cells.
Recall the effector functions of Th2 cells.
Recall the plasticity of T cell subsets of identical clonal origin.
CD8+ T cells kills _______________.
Recall how CD8+ T cells kill target cells.
Recall the effector molecules of CD8+ T cells.
Recall the Bcl-2 family.
Recall how granzyme leads to cell death.
Recall the pathways leading to apoptosis.
Recall the local regulation of T cell effector function by APC.
