Lecture #22 The Lymphatic System Flashcards
What lymphatic vessel is responsible for absorption and transport of ingested lipids?
Lymphatic vessels located in the villi of the gastrointestinal tact (GIT) known as LACTEALS are responsible for absorption and transport of ingested lipids.
Contains nutrients, oxygen, hormones, and fatty acids, as well as toxins and cellular waste products, that are transported to and from cellular tissues
A. Lymph B. Lymphatic vessel C. Lymph nodes D. Spleen E. Thymus
A. Lymph
Serves as the site of T-lymphocyte maturation, development, and control
A. Lymph B. Lymphatic vessel C. Lymph nodes D. Spleen E. Thymus
E. Thymus
Monitors the composition of lymph, the location of pathogen engulfment and eradication, the immunologic response, and the regulation site
A. Lymph B. Lymphatic vessel C. Lymph nodes D. Spleen E. Thymus
C. Lymph nodes
Monitors the composition of blood components, the location of pathogen engulfment and eradication, the immunologic response, and the regulation site
A. Lymph B. Lymphatic vessel C. Lymph nodes D. Spleen E. Thymus
C. Lymph nodes
Transport lymph from peripheral tissues to the veins of the cardiovascular system
A. Lymph B. Lymphatic vessel C. Lymph nodes D. Spleen E. Thymus
B. Lymphatic vessel
What are primary lymphoid organs?
- bone marrow
- thymus
What are secondary lymphoid organs?
- lymph node
- spleen
What is a lymphatic nodule?
Collection of B lymphocytes
- Pale staining central region – germinal center
- When activated in presence of invading microorganism, B cells proliferate producing plasma cells- antibody producing cells
- Macrophages are also found in the germinal center
What is the order of lymph circulation?
Lymphatic capillaries →Lymphatic vessels → Lymph nodes → Lymph trunks → Cisterna Chyli → Lymph ducts → Blood
What is the location for the proliferation and maturation of T-cells?
Thymus
originate from the bone marrow
What part of the thymus contains mainly immature T lymphocytes, is darker staining (due to tightly packed lymphocytes) and also contains special type of cells called Epithelial Reticular Cells (ERCs)?
Cortex
_______________ establish a protective blood-thymus barrier that prevents the developing thymocytes from coming in contact with antigens.
Epithelial Reticular Cells (ERCs)
Which part of the thymus contains more Epithelial Reticular Cells (ERCs)?
The medulla is lighter staining – due to less lymphocyte concentration. Also contains more ERCs.
The thymus contains no afferent lymph vessels (unlike the lymph node). T/F
True
Where are Hassal Corpuscles found?
Hassal Corpuscles (found in the medulla of the thymus)
__________________ mature and differentiate in the bone marrow.
B lymphocytes develop
Lymph nodes have no afferent lymph vessels. (T/F)
False, Lymph nodes have efferent and afferent lymphatic vessels
What is the flow of lymph?
Lymph from afferent lymphatic vessels → Drain into sub capsular sinuses → From the suncapsular sinuses, lymph flow into the trabecular sinuses → Then to the medullary sinuses → And finally exit via the efferent lymphatics in the hilum of the lymph node.
The spleen contains a cortex and medulla. (T/F)
Unlike the lymph nodes, contains no cortex or medulla
What forms the Waldeyer’s ring?
the pharyngeal tonsil, palatine tonsil and lingual tonsil
Where does the right lymphatic duct usually drain?
The right lymphatic duct usually drains into the right subclavian, at its junction with the right internal jugular vein.
The right lymphatic duct drains lymph from which parts of the body?
- Upper right side of the trunk above the diaphragm (via the right bronchomediastinal trunk)
- Right upper limb (via right subclavian trunk)
- Right side of the head and neck (via right jugular trunk)
What drains into the thoracic duct?
Collects and drains lymph from the lower part of the body below the diaphragm, left side of the trunk above the diaphragm, the left upper limb and the left side of the head and neck.
Where does the thoracic duct drain?
It drains/empties into the left brachiocephalic vein.
Thoracic duct is the largest lymphatic vessel in the human body. It usually starts at the level of the 2nd lumber vertebra and extends to the neck.