Lecture 22 Osteoarthritis and Principles of Management Flashcards

1
Q

Name Bimechanical factors of OA

A
Abnormal anatomy 
Intra-articular fracture
Ligament rupture
Meniscal injury
Occupation- farmers, football players
Persistent heavy physical activity
Elite running
Obesity
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2
Q

Name 3 things effects of inflammation in OA

A

Synovial hypertrophy
Subchondral changes
Joint effusion

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3
Q

What biochemical mediators are elevated in OA

A

IL-1B
TNF-a
MMPs

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4
Q

What are features of a clinical diagnosis of OA

A
45+ years
Activity-related joint pain
No morning stiffness or stiffness that lasts no longer than 30 minutes
Rapid deterioration of symptoms
Hot, swollen joint
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5
Q

What are differential diagnosis of OA

A

Gout
Other inflammatory arthritis
Septic arthritis
Malignancy

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6
Q

What is the holistic assessment of person with oA

A
Social- hobbies, duties
Occupational
Mood
Quality of sleep
Support network
Pain assessment
Attitudes to exercise
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7
Q

What are the non-pharmacological treatments of OA

A
  • Thermotherapy
  • Electrotherapy
  • Aids and devices
  • Manual therapy
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8
Q

What are the pharmacological treatments of OA

A
  • Oral analgesia: paracetamol, NSAIDs

* Topical treatments: NSAIDs, capsaicin (knee, hand)

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