Lecture 13 Introduction to Rheumatology and Clinical Aspects of Rheumatoid Arthritis Flashcards
1
Q
Name 5 symptoms of Arthritis
A
Pain, stiffness, swelling, functional impairment and systemic symptoms
2
Q
Name 6 signs of Arthritis
A
Tenderness, swelling, restriction of movement, heat, redness, systemic features
3
Q
What is Rheumatoid arthritis
A
Chronic autoimmune systemic illness characterised by a symmetrical peripheral arthritis
4
Q
What are the genetic aetiologies of Rheumatoid arthritis
A
Amino acid sequences at positions 70-74 DRb1
5
Q
Environmental causes of RA
A
Cigarette smoking, chronic infection e.g. Peridontal disease
6
Q
How is RA diagnosed?
A
Rheumatoid factor- IgG, IgM (redundant test), Anti CCP, ACPA, X-Ray, US
7
Q
Name systemic symptoms of RA
A
Fatigue, weight loss, anaemia, specific (eyes, lungs, nerves, skin, kidneys) Long term (CVS, malignancy)
