Lecture 2.1

Question 1

What is myasthenia Gravis and what are some symptoms?

Answer 1

Muscle weakness that causes fatigue, problems chewing, talking weakness
The conduction of nerve messages are normal, but the immune system destroys ACh receptors

Question 2

What are the 3 types of synapses?

Answer 2

Axodendritic- terminal synapses with dendrite
Axosomatic- Terminal synapses with cell body
Axoaxonic- Terminal synapses with axon

Question 3

What are some possiblities for neurontransmitter re-uptake?

Answer 3

Re-uptake by transporter molecules and dec-activation of Ach by Achetylchoinesterases

Question 4

What are the 4 classes of small molecule neurotransmitters and give examples

Answer 4

Amino acids- Glutamate and GABA
Monoamines- Dopamine, Serotonin, NA
Soluble Gases
Ach

Question 5

What is an agonist and give examples?

Answer 5

Something that increases the activity of the drug
L-Dope increases dopamine
Nicotine increases ACH receptors

Question 6

What is an antagonist and give examples

Answer 6

Something that decrease the activity of a drug
PCPA decreases seratonin
Botulin toxin blocks ACh release