Lecture 19 - Female Genital Tract Flashcards

1
Q

Biopsy Classifications

A

CIN = Cervical Intraepithelia Neoplasia
CIN I - Mild dysplasia
CIN II - Moderate dysplasia
CIN III - Severe carcinoma and carcinoma in situ

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2
Q

Condyloma

A
  • a viral change that HPV produces

- low risk HPV can produce different types: genital warts, flat condylomas (invisible w.out aid of pigment)

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3
Q

LGSIL

A
  • low grade squamous intraepithelial lesion
  • corresponds with CIN I or flat condyloma
  • likely to regress
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4
Q

HGSIL

A
  • high grade squamous intraepithelial lesion
  • corresponds with CIN II and CIN III
  • more likely to progress to carcinoma
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5
Q

Endometriosis

A
  • presence of endometrial glads that line the uterine cavity are found in other areas other than the endometrial caivty
  • repeated bleeding can produce cyctic areas (cysts)
  • can be present anywhere in pelvis (surface of ovary most common)
  • effects 10% of women in reporductive years and 50% of women with infertility
  • possible causes: regulation of mestruated endometrium; metaplasia, and blood/lymphatic spread
  • clincially = scarring, pain, dysuria, dysmenorrhea infertility
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6
Q

Adenomyosis

A
  • similar to endometriosis, just confined to uterus wall
  • presence of endometrium and stroma down in myometrium (where only muscle tissue should be)
  • causes enlargement of uterine wall
  • typically aren’t cystic
  • Cause: menorrhagia, dysmenorrhea, pelvic pain
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7
Q

Menorrhagia

A
  • dysfunctional uterine bleeding caused by endometriosis, adenomyosis, or endometrial hyperplasia
  • prolonged or heavy bleeding during menstration
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8
Q

Metrorrhagia

A
  • irregular bleeding between periods

- dysfunctional uterine bleeding caused by endometriosis, adenomyosis, or endometrial hyperplasia

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9
Q

Fibroids

A
  • aka leiomyoma (leio= smooth, myo = muscle, oma = benign)
  • beign smooth muscle tumors (myometrial tumor)
  • can be subserosal, intramural, or submucosal
  • typically occur in multiples
  • Cause: bleeding, infertility, pain, and pressure
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10
Q

Physiologic Ovarian cysts

A
  • natural cysts of ovary, due to fluid trapped in cavity where ovum was released.
  • more common reason for cysts in ovary
    Two types:
    1. Follicular cysts
    2. Luteal cysts
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11
Q

Follicular cysts

A
  • simple cyst, occurs when microcysts from ovulation build up more fluid and don’t drain/scar as normal (clear fluid)
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12
Q

Luteal cysts

A
  • occurs when PREGNANCY causes cells to change and produce lipids yellow in color
  • causes cyst to appear yellow in color, build up in fluid that doesn’t drain/scar as normal
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13
Q

Surface epithelial tumor names

A
  1. Serous tumors:
    - serous cystadenoma (B)
    - serous cystadenocarcinoma (M)
  2. Mucinous tumors:
    - mucinous cystadenoma (B)
    - mucinous cystadenocarcinoma (M)
  3. Endometrioid tumors (mostly M)
  4. Brenner tumors (mostly B)
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14
Q

Ovarian teratomas

A
  • common tumor (15-20%) of the ovary from germ cells
  • occurs in first two decades of life
  • younger the patient the more likely malignant
  • most benign
    3 Types:
    1. Benign (Mature) Cystic teratoma
    2. Immature malignant teratoma
    3. monodermal teratoma
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15
Q

Benign (Mature) cystic teratoma

A
  • type of ovarian teratoma
  • contains derivations of all three germ cell layers
  • are cystic and contain skin/epidermal structures - “dermoid cyst”
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16
Q

Immature malignant teratoma

A
  • type of ovarian teratoma
  • mostly solid
  • mean age = 18 years
17
Q

Monodermal teratoma

A
  • type of ovarian teratome
  • contains one cell line
  • Example: struma ovarri - from thyroid, not primary ovarian cells
18
Q

Chorioamnionitis

A
  • placental pathology

- inflamation of membranes

19
Q

Funisitis

A
  • placental pathology

- inflammation of umbilical cord

20
Q

Placenta abruption

A
  • placental pathology

- premature separation of placenta from uterine lining

21
Q

Placenta previa

A
  • placental pathology

- placenta overlies cervical opening