Lecture 18 - Pathology of Small Intestine

Question 1

Peptic ulcers never occur on the ____ ____ of the stomach. Ulcers here should be considered ______ until proven otherwise.

Answer 1

Greater Curvature

Malignant

Question 2

Both Cryptosporidia and Giardia infections of the small bowel can lead to diarrhea. What is the mechanism?

Answer 2

They physically block absorption of water.

Question 3

Thyphoid fever which can be caused by Salmonella typhosi, results from rupture/ulceration of hyperplastic _____ ____ (LNs in the small bowel, particularly near the terminal _____).

Answer 3

Peyer’s Patches

Terminal Ileum

Question 4

Small bowel ulceration of the ________ valve is characteristic of TB infection.

Answer 4

Ileocecal valve

Question 5

Mycobacterium avium intracellulari (MAI) is an organism that stains with _____-______ stain (an acid-fast stain) and causes malabsorption disease. It is histologically very similar to ______ disease, but it occurs almost exclusively in _______ patients.

Answer 5

Ziehl-Neelsen

Whipple’s disease

Immunocompromised

Question 6

Malignant ______ (mostly B-cells) can cause malabsorption syndromes in patients. It is typically found in areas of the _______ (geographic region.) It acts very similar to Whipple’s disease, in that the lymphocytes physically prevent absorption of nutrients.

Answer 6

Malignant Lymphoma

Mediterranean