Lecture 18 Flashcards
1
Q
what does 80% of cell RNA consist of?
A
Ribosomal RNA
2
Q
what guides ribose methylation?
A
5’ -> 3’ CUGA
3
Q
what codon and amino acid is the starting signal for translation?
A
AUG codon or Met-M
4
Q
what codons stop translation?
A
UAA, UGA, and UAG
5
Q
what sequence do tRNA have and what end is it on?
A
CCA sequence on the 3’ end
6
Q
what 3 steps initiate translation?
A
small subunit / AUG binding
rRNA recruitment
assembly of initiation complex
7
Q
what are the 4 steps of elongation?
A
tRNA selection
peptide bond formation between amino acids
translocation
release of deacylated tRNA
8
Q
what mutations are responsible for 30% of inherited mutations?
A
nonsense mutations
9
Q
what is the purpose of polyribosomes?
A
increase the rate of protein synthesis
