Lecture 14 Flashcards
Define Genome
the collective
body of genetic
information that is present
in a species
What was Mendel’s 4 conclusions?
- Characteristics are governed by genes
- reproductive cells (gamete) contain one allele for each trait (haploid)
- allele pairs are separated during gamete formation
- alleles undergo independent assortment
what 3 things were examine during the discovery of chromosomes?
Cytoplasm split randomly
Nuclear contents split precisely
material of the nucleus was organized into visible threads
Describe how genes on the same chromosome assort
They do not assort independently and are a linkage group
when does crossing over and recombination occur?
during meiosis
What is the building block of DNA? What makes up this block? what are the difference bases?
nucleotides - made of phosphate, sugar, pyrimidine or purine nitrogenous base
pyrimidine: thymine or cytosine
purine: adenine or guanine
What are some features of nucleotides?
structure is directional (5’ -> 3’)
phosphates link the sugars of nucleotides together (phosphodiester bonds) 5’ phosphate -> 3’ sugar
A = T
G = C
What are the 3 primary functions of DNA?
Store genetic information
capable of replication and inheritance
functionality of genetic message being expressed
What is the structure of DNA?
2 chains of nucleotides running in opposite directions (anti-parallel) forming a spiral
phosphate is exterior of chain while nitrogenous bases are interior
Chains help together by hydrogen bonds between nitrogenous bases
DNA helix completes 1 turn every 10 base pairings