Lecture 16 Cont: II-IV Flashcards

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1
Q

What is the pathogen, reservoir, and vector of west nile virus?

A

Pathogen - west nile virus (Flavivirus)
Reservoir - Birds
Vector - Mosquito

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2
Q

How does the west nile virus operate?

A

invades nervous system and enters blood
high bird mortality but survivors are immune
virus replicates in vector and humans are incidental host

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3
Q

What are the symptoms of west nile virus?

A

fever and neurological diseases

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4
Q

What is the treatment and prevention for west nile virus?

A

no antiviral drugs or vaccine

prevention - limit exposure to mosquitos

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5
Q

Where was zika virus first discovered?

A

Uganda

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6
Q

What kind of pathogen is zika virus? What is its reservoir?

A

Pathogen - zika virus (flavivirus)

Reservoir - primates

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7
Q

What are some kinds of flaviviruses?

A

Yellow fever, dengue fever, west nile

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8
Q

How is zika virus transmitted?

A

mosquito vector or sexual transmission

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9
Q

Why has zika virus been a neglected disease until recently?

A

80% of cases asymptomatic or mild symptoms

Symptomatic cases usually not bad enough to go to the hospital
-ppl rarely die of zika

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10
Q

What is zika virus linked to?

A

Brain damage and microcephaly in pregnant women

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11
Q

What is the prevention/treatment for zika virus?

A

Limit exposure to mosquitoes

no vaccine available

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12
Q

What is the reservoir and transmission for fungal diseases?

A

reservoir - soil

transmission - exposure/infection

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13
Q

What kinds of effects can fungal diseases have?

A

Allergic reactions
Mycotoxins - exotoxins produced by fungi
Mycoses - fungal growth on/in human body

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14
Q

What are the types of mycoses?

A
• Superficial
– Infection on surface layers
– Spread by contact
• Subcutaneous
– Infect deeper skin layers
– Spread by wound infection
• Systemic
– Infection of internal organs
– Primary vs. Secondary infections
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15
Q

How do you treat mycoses?

A

– Antifungal compounds
• Topical + Oral
– Side effects common
– Reduce exposure

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16
Q

What is the american chestnut tree?

A

Abundant
-­50% of Hardwood Forests (East Coast)

Large
-­Up to 100 ft Tall

Valuable
-­Straight-­‐Grained, Rot-­‐Resistant Wood
-­Chestnuts a Cash Crop,
Livestock Feed

17
Q

What is chestnut blight?

A
  • ­‐ Causative Agent: Cryphonectria parasitica
  • ­‐ Ascomycete fungus
  • ­‐ Native to China
18
Q

What is the pathogen, reservoir, and transmission of tetanus?

A

Pathogen - clostridium tetani (fungal disease)
Reservoir - Soil
Transmission - contaminated wounds

19
Q

How does tetanus affect the body?

A

Germination of endospores produce exotoxin called tetanus toxin disrupting the nervous system

20
Q

How is tetanus treated?

A

antitoxin - neutralize toxin already in body

antibiotics - prevent additional toxin production