Lecture 15 Flashcards
How would one figure out the cardiac output in ml/beat?
HR x SV = CO
What is the stroke volume?
The amount of blood pumped from each ventricle per beat
How does one figure out the SV?
The volume of blood in diastolic minus the volume of blood in systole
What is the average blood volume of an adult?
4.5 -5 L
How much L of blood passes through the heart each minute?
The total blood supply in a minute
Is the SA node pacemaker intrinsic or extrinsic?
Intrinsic but is modified by extrinsic control to change pacemaker potential
Is the AP in the heart rate modified by AV node and SNS?
No. The AP stays the same intensity each time
What are the types of extrinsic HR controls?
Neural
Hormonal
Other factors
How does neural control HR?
SNS via thoracic nerve can increase slope of pacemaker potential to reach AP quicker (increase HR)
Ex. Scared, stress
PSNS via vagus nerve lowers HR by longer AP generate
How do hormones control HR?
Epi and norepinephrine
Thyroid hormones - increase HR over days by increase mitochondria numbers and epi receptors
What are other factors that alter the HR?
Ion - high K+ in ISF will decrease HR but can cause heart attack
Fever - increase temp = increase HR
Age - younger = higher HR
Fitness - lower HR from more fit ppl
What is the pathway of the pulmonary artery?
Towards the heart
Pulmonary vein towards lungs
At what condition are the cardiac fibers at optimal length?
Greater stretch the more optimal length for contraction because the more cross bridges formed at max stretch will make a greater force (higher SV)
What is Frank-Starling law?
The force of ejection is proportional to length of ventricle contraction
How can venus return increase?
Exercise (increased rate) or lower HR because it allows the ventricles to fill more