Lecture 14: Osmoregulation on Land Part 2 Flashcards

1
Q

What is the primary role of the kidneys in maintaining homeostasis?
a) Regulating body temperature
b) Maintaining a balance of water, salts, and minerals in the blood
c) Producing metabolic water
d) Excreting carbon dioxide

A

Answer: b) Maintaining a balance of water, salts, and minerals in the blood

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2
Q

How do kidneys contribute to blood pressure regulation?
a) By regulating glucose levels in the blood
b) By filtering large volumes of blood at once
c) By adjusting water and ion concentrations
d) By producing oxygen

A

Answer: c) By adjusting water and ion concentrations

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3
Q

What can happen if the balance of ions (e.g., sodium, potassium, calcium) in the body is disrupted?
a) Increased metabolic water production
b) Malfunction of nerves, muscles, and other tissues
c) Overproduction of urine
d) Reduction in cellular respiration

A

Answer: b) Malfunction of nerves, muscles, and other tissues

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4
Q

Which of the following is a general feature of kidneys across taxa?
a) Production of oxygen during filtration
b) Elimination of aqueous solutions derived from body fluids
c) Direct absorption of nutrients from the blood
d) Excretion of gases such as nitrogen

A

Answer: b) Elimination of aqueous solutions derived from body fluids

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5
Q

How do kidneys differ across taxa?
a) Mammalian kidneys are the only ones that produce filtrate.
b) Amphibian kidneys function primarily for water conservation.
c) The tubular elements and mechanisms vary to meet specific environmental needs.
d) All vertebrate kidneys produce the same concentration of urine.

A

Answer: c) The tubular elements and mechanisms vary to meet specific environmental needs.

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6
Q

What is the role of filtration in kidney function?
a) To secrete solutes into the blood
b) To produce a filtrate of blood by separating waste and useful components
c) To excrete urine directly into the bloodstream
d) To reabsorb solutes from the body fluids

A

Answer: b) To produce a filtrate of blood by separating waste and useful components

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7
Q

Which process involves returning useful solutes from the filtrate back to the blood?
a) Filtration
b) Secretion
c) Reabsorption
d) Excretion

A

Answer: c) Reabsorption

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8
Q

What happens during the secretion phase of kidney function?
a) Waste solutes are removed from the filtrate.
b) Useful solutes are added to the blood.
c) Additional solutes are added to the filtrate from the blood.
d) Water is conserved through osmotic processes.

A

Answer: c) Additional solutes are added to the filtrate from the blood.

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9
Q

If a freshwater fish’s kidneys could not reabsorb ions efficiently, what would likely happen?
a) The fish would retain too much salt in its blood.
b) The fish would excrete urine with a high concentration of ions.
c) The fish would excrete large volumes of very dilute urine.
d) The fish would absorb more salt through its gills.

A

Answer: b) The fish would excrete urine with a high concentration of ions.

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10
Q

. In humans, how does kidney dysfunction affect blood pressure?
a) It causes immediate dehydration and lowers blood pressure.
b) It impairs ion regulation, potentially leading to increased blood pressure.
c) It reduces water reabsorption, causing hypertension.
d) It enhances blood filtration, lowering blood pressure.

A

Answer: b) It impairs ion regulation, potentially leading to increased blood pressure.

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11
Q

What is the function of the fenestrated capillaries in the glomerulus?
a) To reabsorb nutrients from the filtrate
b) To allow selective passage of nitrogenous wastes, water, and solutes while retaining larger elements like red blood cells
c) To secrete ions directly into the filtrate
d) To prevent all fluid from exiting the bloodstream

A

Answer: b) To allow selective passage of nitrogenous wastes, water, and solutes while retaining larger elements like red blood cells

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12
Q

What structure in the nephron collects the filtrate immediately after it passes through the glomerulus?
a) Proximal convoluted tubule
b) Distal convoluted tubule
c) Bowman’s capsule
d) Collecting duct

A

Answer: c) Bowman’s capsule

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13
Q

Which process occurs in the proximal convoluted tubule?
a) Initial filtration of blood
b) Reabsorption of water, ions, and nutrients
c) Secretion of additional solutes into the filtrate
d) Collection of urine for excretion

A

Answer: b) Reabsorption of water, ions, and nutrients

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14
Q

Which animals have a nephron structure similar to that of amphibians and reptiles?
a) Birds and mammals
b) Fish and amphibians
c) Snakes and lizards
d) Mammals only

A

Answer: c) Snakes and lizards

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15
Q

How does the nephron structure of birds and mammals differ from that of amphibians and reptiles?
a) Birds and mammals have longer nephrons for water conservation.
b) Birds and mammals lack Bowman’s capsules.
c) Amphibians and reptiles have a Loop of Henle, while birds and mammals do not.
d) Birds and mammals excrete urine directly into the bloodstream.

A

Answer: a) Birds and mammals have longer nephrons for water conservation.

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16
Q

What is the role of the collecting duct in the nephron?
a) It filters blood plasma.
b) It reabsorbs essential solutes from the filtrate.
c) It collects processed filtrate (urine) from multiple nephrons and directs it to the ureter.
d) It secretes ions into the distal tubule.

A

Answer: c) It collects processed filtrate (urine) from multiple nephrons and directs it to the ureter.

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17
Q

Why does the proximal convoluted tubule have microvilli?
a) To enhance filtration efficiency
b) To increase the surface area for reabsorption of solutes and water
c) To actively secrete toxins into the filtrate
d) To prevent water loss

A

Answer: b) To increase the surface area for reabsorption of solutes and water

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18
Q

What happens to the filtrate as it travels through the intermediate segment (Loop of Henle) in mammals?
a) Solutes and water are actively secreted into the tubule.
b) Water is reabsorbed, concentrating the filtrate.
c) It becomes less concentrated due to passive ion absorption.
d) It remains unchanged until reaching the distal convoluted tubule.

A

Answer: b) Water is reabsorbed, concentrating the filtrate.

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19
Q

What would happen if the fenestrations in the glomerular capillaries become blocked?
a) Filtration would stop, leading to a buildup of wastes in the blood.
b) Reabsorption in the proximal tubule would increase.
c) Urine production would become excessive and dilute.
d) Blood pressure would decrease significantly.

A

Answer: a) Filtration would stop, leading to a buildup of wastes in the blood.

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20
Q

What are the two main layers of the mammalian kidney?
a) Cortex and Bowman’s capsule
b) Cortex and medulla
c) Medulla and renal tubule
d) Glomerulus and collecting duct

A

Answer: b) Cortex and medulla

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21
Q

Where in the kidney are the glomerulus and Bowman’s capsule located?
a) In the medulla
b) In the cortex
c) In the renal pelvis
d) In the renal pyramid

A

Answer: b) In the cortex

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22
Q

Why is the size of the medulla important in mammalian kidneys?
a) It determines the volume of urine that can be produced.
b) It allows adjustment of the length of the renal tubule to conserve water in desert species.
c) It controls the pressure exerted by the glomerulus.
d) It ensures blood pressure regulation within the kidney.

A

Answer: b) It allows adjustment of the length of the renal tubule to conserve water in desert species.

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23
Q

What is the primary function of Bowman’s capsule?
a) To produce urea from nitrogenous waste
b) To collect filtrate from the blood passing through the glomerulus
c) To reabsorb essential nutrients into the bloodstream
d) To secrete solutes into the renal tubule

A

Answer: b) To collect filtrate from the blood passing through the glomerulus

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24
Q

How does the glomerulus filter blood?
a) By secreting enzymes that break down solutes
b) By exerting high blood pressure to force fluid and small solutes through fenestrations
c) By active transport through the capillary walls
d) By selectively absorbing ions into the renal tubule

A

Answer: b) By exerting high blood pressure to force fluid and small solutes through fenestrations

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25
Q

What type of molecules pass through the fenestrations in the glomerular capillaries?
a) Large proteins and red blood cells
b) Water, glucose, amino acids, and urea
c) Hormones and lipids
d) White blood cells and platelets

A

Answer: b) Water, glucose, amino acids, and urea

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26
Q

What is ultrafiltration in the kidney?
a) The selective absorption of solutes in the proximal tubule
b) The active secretion of ions into the nephron tubule
c) The process of blood pressure forcing water and solutes through the glomerulus into Bowman’s capsule
d) The collection of urine in the collecting duct

A

Answer: c) The process of blood pressure forcing water and solutes through the glomerulus into Bowman’s capsule

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27
Q

Which factors contribute to the process of ultrafiltration?
a) Low blood pressure and passive diffusion
b) High blood pressure and fenestrated capillaries in the glomerulus
c) Osmotic gradients and microvilli in Bowman’s capsule
d) Active transport in the collecting duct

A

Answer: b) High blood pressure and fenestrated capillaries in the glomerulus

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28
Q

If blood pressure in the glomerulus drops significantly, what is the likely outcome?
a) Increased filtration of nitrogenous waste
b) Decreased filtration and buildup of waste products in the blood
c) Increased urine production with lower solute concentration
d) Enhanced ultrafiltration due to lower resistance

A

Answer: b) Decreased filtration and buildup of waste products in the blood

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29
Q

What would happen if podocytes in Bowman’s capsule were damaged?
a) Filtration would stop, and blood pressure would increase.
b) Large molecules like proteins might pass into the filtrate.
c) The kidney would be unable to secrete ions into the nephron.
d) Blood flow through the nephron would cease.

A

Answer: b) Large molecules like proteins might pass into the filtrate.

30
Q

What is unique about the mammalian kidney compared to other vertebrates?
a) Mammalian kidneys produce isosmotic urine.
b) Mammalian kidneys produce hyperosmotic urine due to the Loop of Henle.
c) Mammalian kidneys lack a Loop of Henle.
d) Mammalian kidneys excrete urine directly into the bloodstream.

A

Answer: b) Mammalian kidneys produce hyperosmotic urine due to the Loop of Henle.

31
Q

What structural feature of the Loop of Henle allows for the production of concentrated urine?
a) Its short, straight tubule structure
b) Its long tubule, creating a gradient in osmotic pressure between the cortex and medulla
c) Its impermeability to water in both limbs
d) Its lack of active transport mechanisms

A

Answer: b) Its long tubule, creating a gradient in osmotic pressure between the cortex and medulla

32
Q

What type of nephron contains a Loop of Henle?
a) Only mammalian-type nephrons
b) Amphibian and mammalian nephrons
c) All vertebrate nephrons
d) Non-mammalian nephrons

A

Answer: a) Only mammalian-type nephrons

33
Q

What happens in the descending limb of the Loop of Henle?
a) Sodium and chloride ions are reabsorbed via active transport.
b) Water leaves the tubule by osmosis, concentrating the filtrate.
c) Glucose and amino acids are secreted into the tubule.
d) Sodium is actively pumped into the interstitial fluid.

A

Answer: b) Water leaves the tubule by osmosis, concentrating the filtrate.

34
Q

Why is the ascending limb of the Loop of Henle impermeable to water?
a) To ensure water is actively reabsorbed into the blood.
b) To allow active transport of NaCl, creating a concentration gradient in the interstitial fluid.
c) To prevent the filtrate from becoming more concentrated.
d) To reduce the energy required for active transport of solutes.

A

Answer: b) To allow active transport of NaCl, creating a concentration gradient in the interstitial fluid.

35
Q

What is the role of the osmotic gradient established by the Loop of Henle?
a) It allows for active reabsorption of glucose and amino acids.
b) It concentrates the interstitial fluid in the medulla, facilitating water reabsorption from the collecting duct.
c) It dilutes the filtrate to form hypoosmotic urine.
d) It equalizes the osmotic pressure between the cortex and medulla.

A

Answer: b) It concentrates the interstitial fluid in the medulla, facilitating water reabsorption from the collecting duct.

36
Q

What would happen if active transport in the ascending limb of the Loop of Henle were inhibited?
a) The osmotic gradient in the medulla would collapse, and urine would become dilute.
b) The descending limb would stop reabsorbing water.
c) Filtrate would become more concentrated as it ascends.
d) Glucose reabsorption in the proximal tubule would cease.

A

Answer: a) The osmotic gradient in the medulla would collapse, and urine would become dilute.

37
Q

Which protein channels are essential for water reabsorption in the proximal tubule and descending Loop of Henle?
a) Sodium-potassium pumps
b) Aquaporins
c) Chloride channels
d) Urea transporters

A

Answer: b) Aquaporins

38
Q

A desert mammal has an exceptionally long Loop of Henle. What advantage does this adaptation provide?
a) It increases the surface area for glucose reabsorption.
b) It enhances the ability to produce highly concentrated urine, conserving water.
c) It allows the animal to excrete urea at a higher rate.
d) It ensures the production of dilute urine in low-humidity environments.

A

Answer: b) It enhances the ability to produce highly concentrated urine, conserving water.

39
Q

What is the “single effect” in the Loop of Henle?
a) The difference in osmolarity between the filtrate in the descending and ascending limbs of the Loop of Henle
b) The active transport of water in the ascending limb
c) The production of isosmotic urine in the nephron
d) The reabsorption of glucose and amino acids in the proximal tubule

A

Answer: a) The difference in osmolarity between the filtrate in the descending and ascending limbs of the Loop of Henle

40
Q

How is the single effect generated in the Loop of Henle?
a) By the active pumping of NaCl out of the ascending limb into the interstitial fluid
b) By passive diffusion of water into the ascending limb
c) By filtration of solutes into Bowman’s capsule
d) By secretion of solutes into the collecting duct

A

Answer: a) By the active pumping of NaCl out of the ascending limb into the interstitial fluid

41
Q

Why is water unable to follow NaCl out of the ascending limb?
a) Because the ascending limb is impermeable to water
b) Because there is no osmotic gradient
c) Because water is actively transported back into the descending limb
d) Because NaCl diffusion occurs too rapidly

A

Answer: a) Because the ascending limb is impermeable to water

42
Q

What is the primary role of countercurrent multiplication in the Loop of Henle?
a) To establish a horizontal osmolarity gradient across the loop
b) To create a vertical osmolarity gradient in the interstitial fluid of the medulla
c) To dilute the filtrate in the descending limb
d) To directly produce urine in the nephron

A

Answer: b) To create a vertical osmolarity gradient in the interstitial fluid of the medulla

43
Q

During countercurrent multiplication, what happens to the fluid as it moves down the descending limb of the Loop of Henle?
a) Water is reabsorbed, and the filtrate becomes more concentrated.
b) NaCl is actively transported into the interstitial fluid, and the filtrate becomes less concentrated.
c) Glucose and amino acids are secreted into the filtrate.
d) Water is secreted into the filtrate, and osmolarity decreases.

A

Answer: a) Water is reabsorbed, and the filtrate becomes more concentrated.

44
Q

What is the effect of countercurrent multiplication on osmolarity in the ascending limb?
a) Osmolarity increases as solutes are actively transported into the interstitial fluid.
b) Osmolarity decreases as NaCl is actively transported out, and water remains in the filtrate.
c) Osmolarity remains constant due to passive transport.
d) Osmolarity decreases due to the passive diffusion of water.

A

Answer: b) Osmolarity decreases as NaCl is actively transported out, and water remains in the filtrate.

45
Q

How does the single effect contribute to countercurrent multiplication?
a) It increases osmolarity at the top of the Loop of Henle.
b) It creates a horizontal osmolarity difference that is multiplied vertically by fluid movement.
c) It establishes a uniform concentration gradient along the nephron.
d) It increases the concentration of glucose in the filtrate.

A

Answer: b) It creates a horizontal osmolarity difference that is multiplied vertically by fluid movement.

46
Q

If the NaCl pumps in the ascending limb were inhibited, what would happen to the medullary osmolarity gradient?
a) It would increase, concentrating the urine further.
b) It would collapse, resulting in dilute urine.
c) It would remain the same, as water would compensate for the loss of NaCl.
d) It would cause the filtrate in the descending limb to become hypoosmotic.

A

Answer: b) It would collapse, resulting in dilute urine.

47
Q

In countercurrent multiplication, why does the filtrate osmolarity increase as it moves down the descending limb?
a) Because solutes are actively transported into the filtrate
b) Because water is reabsorbed into the interstitial fluid due to its high osmolarity
c) Because NaCl diffuses into the descending limb
d) Because the descending limb actively secretes water

A

Answer: b) Because water is reabsorbed into the interstitial fluid due to its high osmolarity

48
Q

A patient has a damaged Loop of Henle, and their medullary osmolarity gradient is reduced. What effect will this have on their urine concentration?
a) The urine will become more concentrated.
b) The urine will be dilute due to the inability to reabsorb water effectively.
c) The urine concentration will remain unchanged.
d) The urine will become hyperosmotic compared to the blood.

A

Answer: b) The urine will be dilute due to the inability to reabsorb water effectively.

49
Q

How does the collecting duct contribute to urine concentration?
a) It passively secretes water into the urine.
b) It equilibrates with the osmotic pressure of the surrounding interstitial fluid by reabsorbing water through aquaporins.
c) It actively transports NaCl into the interstitial fluid, making the urine hyperosmotic.
d) It prevents water loss by blocking aquaporins.

A

Answer: b) It equilibrates with the osmotic pressure of the surrounding interstitial fluid by reabsorbing water through aquaporins.

50
Q

What happens to water in the collecting duct during diuresis?
a) Water is reabsorbed into the bloodstream.
b) Water remains trapped in the tubule due to low aquaporin levels, leading to dilute urine.
c) Water is actively transported into the interstitial fluid.
d) Water follows sodium into the interstitial space.

A

Answer: b) Water remains trapped in the tubule due to low aquaporin levels, leading to dilute urine.

51
Q

In which condition does the kidney produce highly concentrated urine?
a) Low levels of antidiuretic hormone (ADH)
b) High levels of aquaporins in the collecting duct
c) Increased permeability of the ascending limb of the Loop of Henle to water
d) Reduced osmotic pressure in the interstitial fluid

A

Answer: b) High levels of aquaporins in the collecting duct

52
Q

What is the role of aquaporins in the nephron?
a) To actively transport NaCl into the interstitial fluid
b) To facilitate the passive movement of water across cell membranes
c) To regulate the secretion of solutes into the filtrate
d) To create the single effect in the Loop of Henle

A

Answer: b) To facilitate the passive movement of water across cell membranes

53
Q

How does ADH affect aquaporin activity in the collecting duct?
a) ADH increases the insertion of aquaporins into the membrane, enhancing water reabsorption.
b) ADH blocks aquaporins, preventing water reabsorption and producing dilute urine.
c) ADH removes aquaporins from the membrane, reducing water permeability.
d) ADH stimulates active transport of water into the interstitial fluid.

A

Answer: a) ADH increases the insertion of aquaporins into the membrane, enhancing water reabsorption.

54
Q

Which condition is characterized by low ADH levels?
a) Diuresis, where dilute urine is produced
b) Antidiuresis, where concentrated urine is produced
c) Increased NaCl reabsorption in the collecting duct
d) Water retention in the interstitial fluid

A

Answer: a) Diuresis, where dilute urine is produced

55
Q

What would happen if ADH levels were abnormally high?
a) Water reabsorption in the collecting duct would increase, producing concentrated urine.
b) NaCl transport in the Loop of Henle would increase, producing dilute urine.
c) The osmotic gradient in the medulla would collapse.
d) Aquaporin levels in the collecting duct would decrease, preventing water reabsorption.

A

Answer: a) Water reabsorption in the collecting duct would increase, producing concentrated urine.

56
Q

If the osmolarity of the interstitial fluid in the medulla is reduced, how will urine concentration be affected?
a) Urine will be more concentrated due to reduced water loss.
b) Urine will be dilute because the osmotic gradient driving water reabsorption is disrupted.
c) Urine concentration will increase because of enhanced NaCl transport.
d) Urine concentration will remain unchanged.

A

Answer: b) Urine will be dilute because the osmotic gradient driving water reabsorption is disrupted.

57
Q

What happens in the absence of ADH (antidiuretic hormone)?
a) The collecting duct becomes highly permeable to water, concentrating the urine.
b) The collecting duct becomes less permeable to water, resulting in dilute urine.
c) Aquaporins are inserted into the nephron, increasing water reabsorption.
d) Sodium reabsorption in the proximal tubule decreases.

A

Answer: b) The collecting duct becomes less permeable to water, resulting in dilute urine.

58
Q

Which of the following substances can act as diuretics by interfering with ADH activity?
a) Caffeine and alcohol
b) Antihistamines and glucose
c) Aquaporins and sodium
d) Urea and proteins

A

Answer: a) Caffeine and alcohol

59
Q

In the presence of high levels of ADH, what happens in the collecting duct?
a) Aquaporins are removed, preventing water reabsorption.
b) Aquaporins are inserted into the membrane, increasing water reabsorption.
c) Sodium reabsorption is inhibited, producing dilute urine.
d) Filtrate osmolarity increases due to urea secretion.

A

Answer: b) Aquaporins are inserted into the membrane, increasing water reabsorption.

60
Q

Why do desert animals, like kangaroo rats, have a long Loop of Henle?
a) To produce more dilute urine and conserve solutes.
b) To maximize the osmotic gradient and produce highly concentrated urine.
c) To increase the surface area for glucose reabsorption.
d) To reduce the need for urea excretion.

A

Answer: b) To maximize the osmotic gradient and produce highly concentrated urine.

61
Q

What is the significance of thicker medullas in desert animals compared to aquatic animals?
a) Thicker medullas reduce water reabsorption, producing dilute urine.
b) Thicker medullas allow for a steeper osmotic gradient, enhancing urine concentration.
c) Thicker medullas improve sodium secretion, reducing urine osmolarity.
d) Thicker medullas eliminate the need for ADH regulation.

A

Answer: b) Thicker medullas allow for a steeper osmotic gradient, enhancing urine concentration.

62
Q

Where is osmotic pressure highest in the nephron?
a) Proximal convoluted tubule
b) Distal convoluted tubule
c) Inner medulla near the Loop of Henle
d) Collecting duct in the cortex

A

Answer: c) Inner medulla near the Loop of Henle

63
Q

How does osmolarity change as filtrate moves through the descending limb of the Loop of Henle?
a) Osmolarity decreases as water is reabsorbed.
b) Osmolarity increases as water leaves the tubule and enters the interstitial fluid.
c) Osmolarity remains constant due to sodium reabsorption.
d) Osmolarity decreases due to active transport of NaCl.

A

Answer: b) Osmolarity increases as water leaves the tubule and enters the interstitial fluid.

64
Q

Which of the following waste products is most toxic but requires the least energy to produce?
a) Urea
b) Uric acid
c) Ammonia
d) Carbon dioxide

A

Answer: c) Ammonia

65
Q

What is the primary nitrogenous waste excreted by most aquatic animals?
a) Ammonia (ammonotelism)
b) Uric acid (uricotelism)
c) Urea (ureotelism)
d) Nitrite

A

Answer: a) Ammonia (ammonotelism)

66
Q

Why do terrestrial animals such as mammals primarily excrete urea?
a) Urea is non-toxic and requires less energy than uric acid to produce.
b) Urea can be excreted without water.
c) Urea is highly toxic but requires minimal energy to produce.
d) Urea is the most energy-efficient compound to store nitrogen.

A

Answer: a) Urea is non-toxic and requires less energy than uric acid to produce.

67
Q

Birds and reptiles excrete nitrogenous waste as uric acid because:
a) It is the least toxic and requires the least amount of water for excretion.
b) It is highly soluble in water and can be excreted easily.
c) It is produced without any energy cost.
d) It can be stored in eggs without harming the developing embryo.

A

Answer: d) It can be stored in eggs without harming the developing embryo.

68
Q

Why do aquatic animals typically excrete ammonia instead of urea or uric acid?
a) They lack enzymes for urea production.
b) Ammonia is highly soluble in water and can diffuse directly into the aquatic environment.
c) Urea and uric acid are toxic in aquatic environments.
d) Ammonia allows them to conserve water.

A

Answer: b) Ammonia is highly soluble in water and can diffuse directly into the aquatic environment.

69
Q

During metamorphosis, bullfrogs transition from ammonotelism to ureotelism because:
a) Ammonia becomes toxic in terrestrial environments.
b) Urea production is energetically cheaper.
c) Ammonia cannot be stored in their eggs.
d) Uric acid production is too slow.

A

Answer: a) Ammonia becomes toxic in terrestrial environments.

70
Q

What enzyme activity increases during the bullfrog’s metamorphosis to facilitate urea excretion?
a) Ornithine transcarbamoylase
b) Uricase
c) Ammonia synthase
d) Nitrite reductase

A

Answer: a) Ornithine transcarbamoylase

71
Q

Why do tadpoles primarily excrete ammonia rather than urea?
a) They live in water, which dilutes ammonia quickly.
b) Their enzyme systems for urea synthesis are underdeveloped.
c) Urea synthesis would require the energy they need for growth.
d) All of the above.

A

Answer: d) All of the above.