Lecture #14 - Biotech 2 Flashcards
1
Q
- What does a melanocyte produce and in what 6 regions is it found?
- Melanin - what property of this determines skin color? How is the production of this activated?
- What are freckles?
A
- The AMOUNT of it determines skin colour (the amount of melanin, not amount of melanocytes)
2
Q
So melanin is a _____ of single subunit
A
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3
Q
What is activated in the sun and what can block it?
A
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4
Q
Melanoma:
- What is it? A malignant….
- What is a mole?
- What is the rate of fair skinned people developing melanoma?
- Inherited risk genes are…(2)
- Most cases, melanoma is _____
A
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5
Q
What does keytruda target? What is keytruda?
A
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6
Q
Why do they use virus vectors (2) and how do they engineer them?
Go read the 2nd slide on the 2nd page to see the advantage and disadvantages of the three vectors they have
A
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7
Q
Leber congenital amaurosis
- What is it?
- Increase sensitivity to light is called?
- Involuntary eye movements called?
- What else do they have?
- What’s the rate among new borns?
- How many genes associated with it and what’s the most common?
A
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8
Q
Gene therapy for LCA:
- What vector used?
- What two places did they inject it and tell me about those two and which one was successful
A
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9
Q
Gene therapy for LCA:
- What vector used?
- What two places did they inject it and tell me about those two and which one was successful
A
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10
Q
What are three ways to gene edit?
A
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11
Q
Crispr-cas:
- A system borrowed from where?
- Can be used to what?
A
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12
Q
What’s one solution to stop HIV infection from transmitting? What’s another?
A
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