Lecture 13- Taste Flashcards

1
Q

The mucosa of the body of the tongue comes from

A

branchial arch 1

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2
Q

The mucosa of the root of the tongue comes from

A

branchial arch 3

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3
Q

Warming sensation of the oral mucosa is conveyed by which fibers?

A

C

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4
Q

Cooling sensation of the oral mucosa is conveyed by which fibers

A

A delta

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5
Q

Taste is conveyed by which 3 nerves?

A

CN 7, 9 and 10

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6
Q

Touch sensation of the oral mucosa is conveyed by which fibers

A

Ab fibers (and A delta)

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7
Q

Pain sensation of the oral mucosa is conveyed by which fibers?

A

A delta and C

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8
Q

Innervation of the anterior mouth?

A

CNV

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9
Q

Innervation of the posterior tongue and pharynx

A

CNIX

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10
Q

during eating, volatile molecules from food stimulate the olfactory epithelium by 2 routes

A

orthonasal

retronasal

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11
Q

which route is particularly important for contributing to food flavor

A

retronasal

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12
Q

Taste and olfactory signals enter the brain over separate cranial nerves and then interact extensively in the CNS especially at the…

A

primary gustatory cortex (insula)

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13
Q

in patients presenting at a taste and smell clinic, hypo or ageusia is less common than…

A

olfactory deficits

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14
Q

have many classes of taste receptors do we have

A
5
Sugar- sweet
Amino acids- umami
Salty
Acid- sour
Varied- bitter
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15
Q

Spiciness is not dependent on taste system but is dependent on

A

Pain, TRP receptors

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16
Q

The fungiform papillae are on the dorsal anterior tongue and come from branchial arch…. and are innervated by….

A
  • branchial arch 1

- chorda tympani branch of VII (branchial arch 2)

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17
Q

The… papillae are strategically located to monitor food entering the mouth

A

fungiform

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18
Q

filiform papillae are …shaped and heavily….

A

spine

keratinized

19
Q

Do filiform contain taste buds?

20
Q

filiform are innervated by

A

somatosensory fibers

21
Q

innervation and embryologic origination of foliate

A

CNIX

Branchial arch 3

22
Q

CV taste buds are located in…

A

trench not dorsal surface

23
Q

CV innervated by

24
Q

The functional redundancy of the taste system makes it resilient in the face of

A

partial taste loss

25
taste stimuli are undetectable on the side of the tongue... to anesthesia
ipsilateral
26
chorda tympani anesthesia (unilateral of bilateral) produces .... effects on whole mouth perception
minimal
27
Are the trp receptors for spicy food on taste buds?
no, they are on trigeminal nerve fibers
28
the number of taste papillae.... between individuals
varies greatly
29
bitter receptors are called.... and it is about a 30 member family and it is...
tas2r | G-protein coupled
30
each tasr detects a .... of bitter compounds
limited range
31
differences in the... region determine the number of copies of the sweet receptor that are transcribed. this explains the 16% of the individual variation in how ... sweet substances taste
promoter | intense
32
Variation in sweet receptors affects...
most preferred sugar concentration
33
Fewer sweet receptors= ...
decreased sensitivity
34
light cells of the taste bud have... that reach the taste pore and express receptors for taste substances
microvilli
35
2 types of light cells
type 3 and type 2
36
type 3 light cells respond to.... taste and do they synapse with primary afferent nerve?
sour | yes
37
type 2 light cells respond to .... taste and do they synapse with primary afferent nerve?
- bitter, sweet, aa's | - no
38
type 2 and 3 light cells can be distinguished due to
expression of specific proteins
39
type 2 and 3 light cells use.... to communicate with the primary afferent taste nerves, type 3 uses classic synapses but type 2 do NOT
ATP
40
ATP is released from type .... cells without the aid of a typical synapse using a special voltage-gated channel...
- 2 | - CALHM1 (calcium homeostasis modulator 1)
41
new taste buds differentiate from.... cells and perhaps perigemmal cells just outside the taste bud and give rise to a post-mitotic taste bud "precursor" cell that expresses...
``` (mitotic) basal cells Sonic hedgehog (Shh) ```
42
Shh taste bud precursors are hypothesized to give rise to which cells in the taste bud?
all 3 types
43
Shh is released from the precursor cells and act on surrounding cells to...
maintain taste buds