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Histology SU2017 > Lecture 13- Taste > Flashcards

Lecture 13- Taste Flashcards

1
Q

The mucosa of the body of the tongue comes from

A

branchial arch 1

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2
Q

The mucosa of the root of the tongue comes from

A

branchial arch 3

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3
Q

Warming sensation of the oral mucosa is conveyed by which fibers?

A

C

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4
Q

Cooling sensation of the oral mucosa is conveyed by which fibers

A

A delta

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5
Q

Taste is conveyed by which 3 nerves?

A

CN 7, 9 and 10

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6
Q

Touch sensation of the oral mucosa is conveyed by which fibers

A

Ab fibers (and A delta)

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7
Q

Pain sensation of the oral mucosa is conveyed by which fibers?

A

A delta and C

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8
Q

Innervation of the anterior mouth?

A

CNV

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9
Q

Innervation of the posterior tongue and pharynx

A

CNIX

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10
Q

during eating, volatile molecules from food stimulate the olfactory epithelium by 2 routes

A

orthonasal

retronasal

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11
Q

which route is particularly important for contributing to food flavor

A

retronasal

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12
Q

Taste and olfactory signals enter the brain over separate cranial nerves and then interact extensively in the CNS especially at the…

A

primary gustatory cortex (insula)

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13
Q

in patients presenting at a taste and smell clinic, hypo or ageusia is less common than…

A

olfactory deficits

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14
Q

have many classes of taste receptors do we have

A 
5
Sugar- sweet
Amino acids- umami
Salty
Acid- sour
Varied- bitter
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15
Q

Spiciness is not dependent on taste system but is dependent on

A

Pain, TRP receptors

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16
Q

The fungiform papillae are on the dorsal anterior tongue and come from branchial arch…. and are innervated by….

A
  • branchial arch 1

- chorda tympani branch of VII (branchial arch 2)

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17
Q

The… papillae are strategically located to monitor food entering the mouth

A

fungiform

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18
Q

filiform papillae are …shaped and heavily….

A

spine

keratinized

19
Q

Do filiform contain taste buds?

A

no

20
Q

filiform are innervated by

A

somatosensory fibers

21
Q

innervation and embryologic origination of foliate

A

CNIX

Branchial arch 3

22
Q

CV taste buds are located in…

A

trench not dorsal surface

23
Q

CV innervated by

A

CNIX

24
Q

The functional redundancy of the taste system makes it resilient in the face of

A

partial taste loss

25
Q

taste stimuli are undetectable on the side of the tongue… to anesthesia

A

ipsilateral

26
Q

chorda tympani anesthesia (unilateral of bilateral) produces …. effects on whole mouth perception

A

minimal

27
Q

Are the trp receptors for spicy food on taste buds?

A

no, they are on trigeminal nerve fibers

28
Q

the number of taste papillae…. between individuals

A

varies greatly

29
Q

bitter receptors are called…. and it is about a 30 member family and it is…

A

tas2r

G-protein coupled

30
Q

each tasr detects a …. of bitter compounds

A

limited range

31
Q

differences in the… region determine the number of copies of the sweet receptor that are transcribed. this explains the 16% of the individual variation in how … sweet substances taste

A

promoter

intense

32
Q

Variation in sweet receptors affects…

A

most preferred sugar concentration

33
Q

Fewer sweet receptors= …

A

decreased sensitivity

34
Q

light cells of the taste bud have… that reach the taste pore and express receptors for taste substances

A

microvilli

35
Q

2 types of light cells

A

type 3 and type 2

36
Q

type 3 light cells respond to…. taste and do they synapse with primary afferent nerve?

A

sour

yes

37
Q

type 2 light cells respond to …. taste and do they synapse with primary afferent nerve?

A
  • bitter, sweet, aa’s

- no

38
Q

type 2 and 3 light cells can be distinguished due to

A

expression of specific proteins

39
Q

type 2 and 3 light cells use…. to communicate with the primary afferent taste nerves, type 3 uses classic synapses but type 2 do NOT

A

ATP

40
Q

ATP is released from type …. cells without the aid of a typical synapse using a special voltage-gated channel…

A
  • 2

- CALHM1 (calcium homeostasis modulator 1)

41
Q

new taste buds differentiate from…. cells and perhaps perigemmal cells just outside the taste bud and give rise to a post-mitotic taste bud “precursor” cell that expresses…

A 
(mitotic) basal cells
Sonic hedgehog (Shh)
42
Q

Shh taste bud precursors are hypothesized to give rise to which cells in the taste bud?

A

all 3 types

43
Q

Shh is released from the precursor cells and act on surrounding cells to…

A

maintain taste buds

Histology SU2017 (14 decks)

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