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Histology SU2017 > Lecture 11- Alveolar Bone (Sun) > Flashcards

Lecture 11- Alveolar Bone (Sun) Flashcards

1
Q

RANKL stimulates…

A

osteoclast differentiation and maturation

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2
Q

OPG binds to… and…

A

RANKL

indirectly inhibits osteoclast differentiation

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3
Q

3 major functions of osteoblasts

A
  1. synthesize and secrete ECM
  2. regulate matrix mineralization
  3. Regulate osteoclasts through molecular interactions
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4
Q

3 functions of osteocytes

A
  1. regulate osteoblasts and clasts through cell processes
  2. maintain bone vitality and function
  3. sense mechanical loading
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5
Q

which cell type has a tartrate resistant acid phosphatase (TRAP) positive cytoplasm?

A

osteoclast

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6
Q

3 functions of osteoclasts

A
  1. demineralize bone
  2. degrade organic matrix
  3. endocytosis of degraded products
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7
Q

which has a higher remodeling rate? trabecular or cortical bone

A

trabecular

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8
Q

Which cycle duration is longer, formation or resorption

A

formation

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9
Q

unbalanced bone formation/resorption causes?

A

osteoporosis

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Histology SU2017 (14 decks)

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