Lecture 11- Alveolar Bone (Sun) Flashcards
1
Q
RANKL stimulates…
A
osteoclast differentiation and maturation
2
Q
OPG binds to… and…
A
RANKL
indirectly inhibits osteoclast differentiation
3
Q
3 major functions of osteoblasts
A
- synthesize and secrete ECM
- regulate matrix mineralization
- Regulate osteoclasts through molecular interactions
4
Q
3 functions of osteocytes
A
- regulate osteoblasts and clasts through cell processes
- maintain bone vitality and function
- sense mechanical loading
5
Q
which cell type has a tartrate resistant acid phosphatase (TRAP) positive cytoplasm?
A
osteoclast
6
Q
3 functions of osteoclasts
A
- demineralize bone
- degrade organic matrix
- endocytosis of degraded products
7
Q
which has a higher remodeling rate? trabecular or cortical bone
A
trabecular
8
Q
Which cycle duration is longer, formation or resorption
A
formation
9
Q
unbalanced bone formation/resorption causes?
A
osteoporosis