Lecture 13 - Linkage and Quantitative Genetics Flashcards
1
Q
Haplotypes
A
haploid genotypes, the multilocus genotype of a chromosome or gamete
2
Q
Linkage equilibrium
A
When the genotype of a chromosome at one locus is independent of its genotype at the other locus.
3
Q
Linkage disequilibrium
A
When there is a nonrandom association between a chromosome’s genotype at one locus and its genotype at the other locus
4
Q
What 3 mechanisms cause LD in random-mating populations?
A
- Selection on multilocus genotypes
- Genetic drift
- Population admixture
5
Q
Genetic recombiantion
A
The creation of new combinations of alleles during sexual reproduction
6
Q
Extended haplotype homozygosity (EHH)
A
a measure of linkage disequilibrium between an allele at a locus of interest and allele at other loci on the same chromosome.
