Lecture 12 Flashcards
What is gene regulation
selective control by cells
human genome size
3.2 billion BP’s, 20,000 genes
fly genome size
122.7 million BP’s, 15,500 genes
human genome vs fly genome
human genome is 30x larger but only 1.3x more genes
human genome is mostly
regulatory not coding
E. coli genome size
5.44 million BP’s, 5400 genes
Metabolism is
catabolism and anabolism
catabolism is
the breaking down of molecules into raw materials
always off, initiated by pressence of molecule
anabolism is
the building of molecules from raw materials
always on, repressed by buildup of molecules
Lac Operon is made up of
LacZ, LacY, LacA
LacZ gene does what
encodes for ß-galatosidase which breaks down lactose into simple sugars
LacY gene does what
encodes for galatosidase permeate which brings lactose into cell
LacA gene does what
encodes for trans-acetylase which adds an acetyl group to lactose
LacI does what
builds repressor protein which inhibits RNA pol activity
Lac operon is an example of what
catabolism