Lecture 11: Blood Flashcards
What is blood classified as? Describe its function
Blood is a form of specialized CT
Function: transportation of nutrients and end products, regulation and protection
What is blood composed of ?
- Erythrocytes
- Leukocytes
- Platelets
- PLASMA
What is the function of plasma?
Maintain osmotic pressure, transport clotting and immune function
What are the protein solutes in plasma and what are their respective functions?
Albumin- Maintains osmotic pressure
Globulin- Includes immunoglobulins and antibodies
Fibrinogen- Proteins that participate in blood coagulation
Where do the several blood cell types originate from?
CT of bone marrow
What are the classifications of leukocytes?
- Agranular leukocytes → T and B lymphocyte production+ monocyte
- Granular Leukocyte→ neutrophils, basophils and eosinophils
What are the key features of RBC?
ERYTHROCYTES!
- produced via erythropoiesis
- Function: oxygen and carbon dioxide transport
- Biconcave disk: increased SA to V ratio
- O2 carrying haemoglobin
How long do erythrocytes last and what happens to them after that period of time?
Last around 120 days → removed in the spleen, bone marrow and liver by phagocytosis
What are the 4 main blood groups and what antibodies and antigens to they present
- Blood group A → Anti-B antibody and A antigens
- Blood group B → Anti- A antibody and B antigens
- Blood group AB → No antibodies and A/B antigens
- Blood group O → Anti A and anti B antibodies and no antigens
What are the rules of blood donations/transfusions?
Blood can be received if they have the same antigens
Rh+ can receive from other Rh+ and Rh-
Rh- can ONLY receive from Rh-