Lecture 11 Flashcards
How does the nervous system produce movement and respond to sensation?
- Functional anatomy of movement
- Basal ganglia and cerebellum
- Vestibular system
- Somatosensory system
Main components of the motor system
- Forebrain: initiating movement
- Brain stem: species-typical movement
- Spinal cord: executing movement
Main motor assisting brain regions
- Basal ganglia (forebrain): help to produce the appropriate amount of force
- Cerebellum (brainstem): regulate timing and accuracy
3 stages of movement execution
Planning: prefrontal cortex
Organisation: premotor cortex
Execution: primary motor cortex
Planning - prefrontal cortex
Specify goal and decide to execute a movement
Organisation - premotor cortex
Specify precise complementary movements needed to execute the plan (organise motor sequences)
- Preprogrammed set of movements produced as a single unit
Execution - primary motor cortex
Translate motor sequences into motor commands that produce specific movements (specialised in focal skilled movements)
Simple movement
Blood flow increased in the hand area of hte primary somatosensory and primary motor cortex when subjects used a finger to push a lever.
- M1 and S1
Movement sequence
Blood flow increased in the premotor cortex when subjects performed a sequence of movements
- M1 and S1
- Dorsal premotor
Complex movement
Blood flow increased in the prefrontal and temporal cortex when subjects used a finger to find a route through a maze
- M1 and S1
- Dorsal premotor
- Prefrontal (goal)
- Temporal (what)
- Parietal (how)
Hierarchical and parallel control organisation
H = prefrontal > premotor > primary motor
P = plan and execute multiple independent movements simultaneously
What does it mean that motor movements are spatially coded > somatotopic arrangement?
Body part relative sizes are disproportionate
- More extensive areas of M1 allow precise regulation of movements
Body parts are discontinuous
- Arranged different from those of our actual body
Corticospinal tract
- originates mainly in motor cortex layer V
- ends in anterior horn of spinal cord
- aka pyramidal tract, axon crossing in medulla (brain stem)
corticospinal tract - 2 descending pathways
- lateral corticospinal tract: crosses in medulla, brainstem
- ventral (anterior) corticospinal tract: uncrossed
lateral corticospinal tract
- crosses over to the contralateral side
- ends at the lateral region of the contralateral anterior horn
- distal musculature
- NB: mainly lateral interneurons and motor neurons