Lecture 10 - Haematuria & Proteinuria Flashcards
Proteinuria & tests?
mainly albumin; 24 hour urine, albumin:creatinine & protein:creatinine
Microalbuminuria diagnosis?
30-300mg albumin/day; 2.5-25mg/mmol albumin:creatinine ratio
Microalbuminuria causes?
diabetes, fever, exercise, heart failure
Nephrotic syndrome and pressures?
low albumin, low oncotic P (derived from plasma proteins), and high hydrostatic pressure, water pushed from intravascular compartment into tissue
Nephrotic syndrome and fats?
low plasma oncotic pressure increases lipoprotein production by liver, increasing cholesterol production; VLDL and LDL metabolism is also reduced
Nephritic syndrome presentations?
AKI, hypertension, RBC in urine, RBC casts
Nephrotic Syndrome Presentations?
oedema, proteinuria, renal function normal or impaired
Glomerula Haematuria?
often microscopic, often paired w proteinuria
Haematuria from collecting systems?
usually macroscopic, no/little proteinuriaq
Spread of renal cancer?
local spread not common, mainly blood-borne metastases