Lecture 1: Respiratory Cycle and Mechanics Flashcards
What does Boyle’s law say?
Pressure of gas is inversely proportional to volume
What happens when lung volume increases?
Pressure in lungs decrease so air can enter lungs
What happens when lung volume decreases?
Pressure in lungs increases so air can exit lungs
What happens during inspiration?
- Inspiratory muscles (external intercostal muscles) contract
- Diaphragm descends
- Thoracic volume increases
- Intrapleural pressure and alveolar pressure decreases
- Chest wall and lungs will expand due to coupling (lungs want to collapse)
Where is parietal fluid found?
Between parietal and visceral pleura
What is intrapleural pressure?
Pressure everywhere in thorax except lumens of blood vessels, lymphatics, and airways
What is the intrapleural pressure at rest?
-5 cm H2O
What is the intrapleural pressure during inspiration?
Reaches -8 cm H2O
What is the alveolar pressure at rest?
0 cm H20
What is the alveolar pressure during inspiration?
-1 cm H20
What happens during inspiration?
- Passive so expiratory muscles not always used
- Diaphragm ascends
- Thoracic volume decreases
- Intrapleural pressure and alveolar pressure increases
- Chest wall and lungs will shrink due to coupling
What is the intrapleural pressure during expiration?
Goes back to rest (-5 cm H2O)
What is the alveolar pressure during expiration?
Reaches +1 cm H2O
What four things does the respiratory cycle show change in?
1) Volume
2) Alveolar Pressure
3) Intrapleural Pressure
4) Air Flow
What is minute ventilation?
What is the normal value?
Volume of air inhaled every minute