Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Summer Pharmacology 2 > Lecture 1: Anti-Fungal, Helminth, Protozoa, Viral > Flashcards

Lecture 1: Anti-Fungal, Helminth, Protozoa, Viral Flashcards

1
Q

Luminal anti protozoa amebicide that causes peripheral neuropathy as a side effect

A

Iodoquinol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Drug used to remove worms from the GI tract

A

Emetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

DOC for systemic fungal infections

A

Amphotericin B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Anti helminthic agent that Stops microtubule synthesis and glucose uptake, effective against nematodes, after positive scotch tape test

A

Mebendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Mixed action anti protozoal used as the DOC for pseudo membranous colitis and stds like giardiasis, trachomonas, and anaerobic gram neg bacilli, metallic taste, only one dose in men because they are less compliant

A

Metronidazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Second line for CMV retinitis, causes dose dependent neutropenia, effective but resistant strains are emerging, CI in renal failure

A

Gancyclyovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Broad spectrum anti fungal that interacts with other drugs but is safe in patients with liver and kidney impairment

A

Possaconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Anti helminthic that is used to treat cutaneous larva, affects microtubule aggregation, causes Stevens Johnson syndrome, dizzy, vomit, anorexia

A

Thiabendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Guanasine analog effective in treating HBV that is resistant to Lamivudine

A

Entecavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Neuromuscular blocking agent that paralyzes worms, used in combo with mebendazole, causes vomiting and diarrhea

A

Pyrantel pamoate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Derived from ginghausum plant, this anti malaria drug is not used by practicing physicians and saved as the last resort to prevent development of resistance

A

Artemisin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

DOC for infection of cestodes, but but only kills the scolex so a laxative is needed with it

A

Nicosamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

First approved nucleotide analog for HIV treatment

A

Tenofovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

First line for CMV retinitis, best for AIDS patients and causes neutropenia, metabolic acidosis, and ocular hypotony

A

Cidofovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Luminal amebicide like that is also an aminiglycoside antibiotic

A

Paromomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Treatment for acute herpes zoster infections

A

Famciclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Anti fungal that binds to ergosterol, can be send in combo with Amphotericin B, treats systemic mycosis and meningitis

A

Flucytosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

NRTI HIV therapy used when pt are intolerant to more main stream tx

A

Abacavir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

NNRTI for HIV tx bins with albumin 98% and excreted in both urine and feces

A

Delavirdine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

DOC for Leishmaniasis

A

Sodium Stobogluconate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Primary drug used to treat trypanosomiasis, a frequent cause of pneumonia in HIV pts

A

Pentamidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Anti malaria drug reserved for severe infestations, causes chinconism, potentials digoxin

A

Quinine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Synthetic Anti fungal that inhibits ergosterol formation

A

Ketoconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Drug used topically to treat superficial candida infections

A

Nystatin

25
Q

Treatment for HBV, besides vaccine

A

Interferon and lamivudine

26
Q

Anti fungal that is used to treat AIDS histoplasmosis, blastomycosis, sporotrichosis, para coccidiomycosis, but causes gynecomastia as a side effect, typically in farmers of flowers

A

Itraconazole

27
Q

DOC for neoformans, candidemia, coccidiomycosis, inhibits formation of ergosterol, teratogenic

A

Fluconazole

28
Q

Anti folate agent that treats both malaria and toxoplasmosis

A

Pyremethamine

29
Q

HCV treatments (2)

A

Interferons and ribavirin

30
Q

DOC for malaria, interferes with nutrition, destroys infected RBCs

A

Chloroquine

31
Q

4th line treatment for CMV retinitis, intravitreal injection, not for pt. with AIDS

A

Fomiversen

32
Q

NRTI HIV treatment for cases with AZT resistance, SE fatal pancreatitis, dose limiting peripheral neuropathy

A

Didanosine

33
Q

Mixed action anti protozoal similar to metronidazole but second gen and more expensive

A

Tinidazole

34
Q

Anti fungal that functions by binding to ergosterol, can be combined with Flucytosine

A

Amphotericin B

35
Q

Topical anti fungal that can be combined with nystatin

A

Miconazole

36
Q

Third line for CMV retinitis, for strains that are resistant to second line (Gancyclyovir), dose dependent due to reversibility between DNA and RNA polymerase.

A

Foscarnet

37
Q

HIV treatment, pyrimidine, protective in fetus of infected mothers during pregnancy, toxicity potentiated but several drugs, effectiveness decreases with time

A

Zidovudine

38
Q

HIV tx when intolerant to zidovudine (2)

A

Stavudine or zalcitabine

39
Q

Drug used to treat both HBV and HIV, has a 9 hour half life

A

Lamivudine

40
Q

Anti fungal DOC for aspergillosis,SE transient visual disturbance

A

Voriconazole

41
Q

HBV treatment that functions by terminating DNA replication

A

Adefovir

42
Q

Cestodes treatment that inhibits microtubule synthesis and glucose uptake, can work on nematodes but mostly used for cestodes

A

Albendazole

43
Q

Topical acyclic guanoside for HSV 1/2 and VZ, 30X stronger than acyclovir, apply with spatula

A

Pencyclovir

44
Q

HIV treatment used in combo with zidovudine

A

Lamivudine

45
Q

DOC for river blindness (onchocercosis) and scabies. Causes paralysis in parasites, kills worms via mezzoti like reaction, contraindicated in pts using barbiturates or benzodiazepines because of action on GABA receptors

A

Ivermectin

46
Q

DOC for Trematodes causing schistosomiasis and Cistercosis, decrease membrane permeability to calcium, causing paralysis, not for ocular Cistercosis because it an damage the eye. Not for pregnant or lactating

A

Praziquantel

47
Q

DOC for Giardiasis, the most common cause of diarrhea in the world.

A

Metronidazole - also for pseudo membranous colitis

48
Q

DOC for toxoplasmosis (from eating red meat)

A

Pyrimethamine ( also anti folate malaria)

49
Q

Anti viral drug to treat HSV1/2, VZ, and EBV, requires kidney function test, applied to skin with spatula

A

Acyclovir

50
Q

DOC for dermatophyts in skin and nail and superficial mycosis,

A

Terbinafine

51
Q

NNRTI for HIV with 14 day titration period with half dose reduction to eliminate epidermal reactions

A

NNRTI for HIV treatment with 99% coupling to albumin, half life of 40 hours

52
Q

exclusive treatment for candida infections, last resort to avoid resistance

A

Echinocandins: caspofungin and micafungin

53
Q

DOC for parasitic infection by filiaris

A

Diethylcarbamazine

54
Q

Anti malaria drug used when strains are resistant to p. Falciparum

A

Mefloquine

55
Q

Fungicidal used for athletes foot and jock itch, accumulates in high fat tissue, contraindicated in acute intermittent porphyria, gets you drunk faster from alcohol, destroys mitosis spindles

A

Griseofulvin

56
Q

Drug to treat diarrhea caused by giardiasis , shorter course and more expensive than metronidazole

A

Tinidazole

57
Q

Once a day HIV treatment

A

Emtricitabine

58
Q

Tissue schizontocide used to eliminate the Exo erythrocytes form of Malaria

A

Primaquine

Summer Pharmacology 2 (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions