Lect 6 - Infant Growth and Development Flashcards

1
Q

Intra-uterine growth

A

Embryonic/fetal growth; assessed by birthweight

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2
Q

Gestational age

A

Age since 1st day of last menstrual period (post-menstrual age)

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3
Q

Full-term

A

38-42 weeks post-menstrual age

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4
Q

Low birthweight

A

<2500 g

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5
Q

What is assessed at delivery of the infant?

A

Measurement of length, weight, head circumference
- Assessed with growth charts

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6
Q

What are the cut-offs for intra-uterine growth patterns (SGA, AGA, and LGA)?

A
  • SGA: <10th percentile
  • AGA: 10-90th
  • LGA: >90th
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7
Q

Infant factors leading to SGA

A

Congenital anomalies, genetic conditions, congenital infections

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8
Q

Placental factors leading to SGA

A

Small placenta, inadequate placental blood flow

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9
Q

Maternal factors leading to SGA

A

Smoking, alcohol, drugs, undernutrition

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10
Q

Risks associated by SGA

A
  • hypoglycemia
  • inability to maintain temp (not enough fat)
  • decreased immune competence
  • neurological and behavioural problems

(Related to in utero adaptations)

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11
Q

Infant and maternal factors leading to LGA

A

Infant: genetic
Maternal: uncontrolled diabetes

Risk factors are different for normal LGA and baby of diabetic mother

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12
Q

Risks associated with LGA

A

All: birth injury
Infants of diabetic mothers: hypoglycemia, hypocalcemia, respiratory, cardiac, cognetial problems

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13
Q

When do growth patterns require a follow up?

A
  • flat growth line (not following growth curve)
  • Sharp increase or decrease
  • below 3rd percentile
  • above 97th percentile (weight for length)
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14
Q

Corrected age for premature infants:

A

Current age - (40 - gestational age) = Corrected age

Assumes full term is 40 weeks

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15
Q

Physiological adaptation to post natal life

A

Gastrointestinal function
- GI formed before 3rd trimester and amniotic fluid is ingested in the 3rd trimester, preparing GI for nutr
- GI motility mostly developed
- Infants can digest breastmilk efficinetly (high disaccharidases, low pancreatic amylase for starch, slightly low fat digestion)

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16
Q

Glomerular filtration rates (birth, 1 year, 3 years)

A

Birth: 30%
1 year: 70%
3 years: 100%

In relation to adult levels

17
Q

Renal solute load

A

Electrolytes and urea that need to be excreted. Requires more water.

Increased by high protein

18
Q

Protective adaptations in post natal life

A

Mucosal barrier function. Includes protective mechanisms in infant gut:
- gastric barrier, proteolysis, peristalsis, factors in breastmilk
- mucosal coat and microvillus membrane
- antibodies (IgG, sIgA), other substances

19
Q

Major metabolic change at birth

A

Loss of a constant supply of glucose. Glycogen and triglyceride synthesis begin in the 3rd trimester. Plasma glucose decreases at birth and insulin reduces, glucagon increases.

20
Q

AGPAR score

A

Appearance: skin colour
Pulse: heart rate
Grimace: response to stimulation
Activity: flexion (activity and muscle tone)
Respiration: Respiratory effort
5 numbers are added together
- 8-10 is good
- 5-7 may require some breathing help
- 4 or less require immediate help

Does not determine long term health

21
Q

Primitive reflexes (4)

A

Rooting: head turning towards stroked face
Sucking: reflexive, not voluntary
Moro: “startle” reflex - arms move outwards and then towards body
Head lag/step: head movement during pull to sit, stepping movement when held upright

22
Q

What is needed for milk feeding and baby food?

A

Milk feed: grasp nipple, suck, swallow, breathe
Baby food: tongue movement to move food back, upright posture and head control

23
Q

What is needed for self feeding?

A

Finger foods: grasp, hand to mouth, tongue movement to side, upright posture and head control
Cup drinking: hand and object to mouth, tilt head and cup backwards, control free flowing liquid

24
Q

Developmental milestones (Birth, 4-6 mos, 6 mos)

A

Birth: grasp nipple, suck, swallow
4-6 mos: grasp objects, improved head control, some vocalization
6 mos: transfers objects from hand to hand, hand to mouth, sit with support, 1st teeth, expresses food preferences

25
Q

Developmental milestones (7-8 mos, 9 mos, 12-15 mos)

A

7-8 mos: sit independently, more vocalization
9 mos: pincer grasp, cruising on furniture
12-15 mos: walking, words, 1st molars