lect 6- bact. genome replication, expression and reg 2 Flashcards
define global regulation
regulatory systems that affect many genes and pathways simultaneously
define regulon
genes or operons controlled by common regulatory protein
define modulon
operon network under control of common global regulatory protein but individual operons are controlled separately by their own regulators
define activator
enhances transcription needed
define repressor
inhibits transcription unless needed
what are the 2 proteins involved in 2 component regulatory system
sensory kinase and response-regulator protein
define EnvZ
sensory kinase: autophosphorylates in high osmolarity
define OmpR
response regulator: phosphorlyated and regulates transcription
what does sigma factor 70 do
transcribes genes that are needed during exponential growth
what does CheY do
governs rotation of flagella
is CheA.CheW active/phosphorylated when attractant concentration is high or low
when it is high
what does LuxR do
stimulates transcription of the genes for AHL synthase (luxe) and proteins needed for light production
define auxotrophic mutant
unable to make an essential macromolecule such as an aa or nucleotide
what corrects errors in DNA/does proofreading
DNA polymerase
what is photoreactivaiton direct repair used for
to directly rem air thymine dimers
