lect 4- viruses and other a cellular infectious agents Flashcards

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1
Q

viruses differ from bacteria in that viruses…

A

are not composed of cells

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2
Q

what distinguishes a chronic viral infection from a latent viral infection

A

infectious virus gradually builds up over a long period of time

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3
Q

define virus

A

protein and nucleic acid

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4
Q

define viroids

A

only RNA

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5
Q

define satellites

A

only nucleic acids

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6
Q

what is the envelope of viruses a combination of

A

lipids, proteins and carbs

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7
Q

what proteins are capsids made of

A

protein subunits called protomers or capsomers

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8
Q

what is the largest animal viruses

A

poxviruses

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9
Q

what is the order for multiplication of animal viruses

A

attachment, penetration/entry, uncoating, biosynthesis, maturation, release

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10
Q

what are the 3 methods for viral entry

A

fusion, endocytosis and injection of nucleic acid

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11
Q

what is the classification of a virus based on

A

nucleic acid type, presence/absence of envelope, capsid symmetry, dimensions of vision and capsid

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12
Q

describe an acute infection

A

rapid multiplication–> cell death and virus release

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13
Q

describe latent infection

A

viral components are present; host is not harmed –> activation –> cell death and virus release

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14
Q

describe chronic infection

A

slow release of virus without cell death

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15
Q

describe transformation into malignant cell

A

activation of host proto-oncogenes or insertion of oncogene

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16
Q

what are the possible mechanisms by which viruses can cause cancer

A

viral proteins bind host cell tumor suppressor proteins, carry oncogene into cell and insert it into host genome, altered cell regulation, insertion of promoter or enhancer next to cellular oncogene

17
Q

what can cause plant diseases

A

viroid

18
Q

define satellites

A

encode their own capsid proteins when helped by a he per virus (do NOT encode their own capsid proteins)