lect 23 Flashcards

1
Q

what is log Kow and pharmacology?

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2
Q

what is the example of Log Kow, how to find Csat?

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3
Q

what does calculated (C) log Vp enable?

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4
Q

what is the estimation of low Kow?

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5
Q

what equation can we used to predict log Kow?

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6
Q

what are the contributions to log Kow?

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7
Q

what do we refer to for log Kow and molecular structure?

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8
Q

what are some common fragment constants useful for Log Kow estimation?

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9
Q

what are some common intramolecular interactions factors useful for log Kow estimation?

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10
Q
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11
Q

what is benzene?

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12
Q

what is nitrobenzene?

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13
Q

example: hexane log Kow calculation?

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14
Q

what is the branching or ring structure cyclohexane example?

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15
Q

what are the differences in nitromethane and nitrobenzene?

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16
Q

what are the measured log Kow of benzene and nitrobenzene?

17
Q

what are polar functional groups?

18
Q

what are intramolecular correction factors for Kow fragment constants?

19
Q

what is calculating Kow?

21
Q

differences between benzene and cyclohexane?

24
Q

what is electronic factors in table 7.4?

25
Q

what is tetrachloroethylene?