lec5 : blood groups Flashcards

1
Q

any substance recognized by the body as

foreign

A

Antigen

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2
Q

Antigen on the surface of RBCs

A

agglutinogens

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3
Q

the most important and best known agglutinogens are the ……………

A

A and B agglutinogens

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4
Q

Antibodies against red cell agglutinogens are called

………………. and they are present in ……………..

A

agglutinins

plasma

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5
Q

Frequency in population of BG A ……….

A

41%

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6
Q

Frequency in population of BG B ……….

A

10 %

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7
Q

Frequency in population of BG AB ……….

A

4 %

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8
Q

Frequency in population of BG O ……….

A

45 %

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9
Q

When A or B antigen meet its corresponding antibody, ……………………………………………………

A

agglutination reaction occurs.

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10
Q

In agglutination reaction , RBC …………………………….

A

clump and stick to each other then hemolyse

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11
Q

WHY The agglutinins attach themselves to the RBCs?

A

Because agglutinins have many binding sites, a single

agglutinin can attach to different red cells at the same time

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12
Q

“Rh‐positive” found in…………………… of population.

A

85-90%

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13
Q

The population are divided according to presence of ………………… into Rh‐positive and Rh‐negative

A

D‐Antigen

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14
Q

Hemolytic disease of the New‐born

A

Erythroblastosis Fetalis

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15
Q

t is a condition due to Rh‐incompatibility between mother and fetus blood

A

Erythroblastosis Fetalis

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16
Q

to prevent sensitization of a Rh‐negative mother,
she is given a single dose of …………………………… in the first……………… after
delivery starting from ………….. delivery

A

anti‐Rh antibodies (Anti‐D immune globulin)
48 hours
first